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一种用于电阻抗断层成像的开源且易于复制的硬件。

An open-source and easily replicable hardware for Electrical Impedance Tomography.

作者信息

Brazey B, Haddab Y, Zemiti N, Mailly F, Nouet P

机构信息

LIRMM, Univ Montpellier, CNRS, Montpellier, France.

出版信息

HardwareX. 2022 Feb 10;11:e00278. doi: 10.1016/j.ohx.2022.e00278. eCollection 2022 Apr.

Abstract

Electrical Impedance Tomography (EIT) is a powerful imaging tool for investigating electrical properties of tissues such as that of human bodies. The cheap, harmless and portable nature of this tool has made EIT a popular choice in many biomedical applications. However, performing EIT requires strong development at both hardware and software levels. In particular, performing in-lab experiences remains a challenge due to the cost of commercially available devices or the complexity of systems proposed in scientific literature. In this paper, an efficient and easily replicable EIT hardware is presented. This hardware was developed with the objective of making EIT accessible to as many people as possible. It has been designed for operating frequencies between 1 kHz and 50 kHz, and can be used for in-lab validation of proof of concept. Special care has been paid to the choice of components in order to optimize the performance versus cost ratio. Also, the overall footprint has been reduced by using recent and up-to-date integrated circuits. In particular, the use of a lock-in amplifier is a compact solution that allows both narrow-band filtering of the signal and provides an easily quantifiable DC signal at the output. Circuit schematics as well as manufacturing files are shared so that understanding, replication and improvement of circuits are facilitated. Fabrication and usage procedures are given as well. At last, the proposed hardware is experimentally tested and validated first by comparing experimental data to simulations, then by reconstructing an inclusion in biological tissues.

摘要

电阻抗断层成像(EIT)是一种用于研究人体等组织电学特性的强大成像工具。该工具具有成本低、无害且便携的特点,使其在许多生物医学应用中成为热门选择。然而,执行EIT需要在硬件和软件层面进行大量开发。特别是,由于商用设备的成本或科学文献中提出的系统的复杂性,进行实验室实验仍然是一个挑战。本文介绍了一种高效且易于复制的EIT硬件。开发此硬件的目的是让尽可能多的人能够使用EIT。它被设计用于1kHz至50kHz的工作频率,可用于实验室概念验证。在组件选择上特别注意优化性能成本比。此外,通过使用最新的集成电路减少了整体占地面积。特别是,使用锁相放大器是一种紧凑的解决方案,它既允许对信号进行窄带滤波,又能在输出端提供易于量化的直流信号。共享了电路原理图以及制造文件,以便于理解、复制和改进电路。还给出了制造和使用程序。最后,通过将实验数据与模拟结果进行比较,然后在生物组织中重建一个内含物,对所提出的硬件进行了实验测试和验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aada/9058698/56d2b590ad54/gr1.jpg

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