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5 年功能后使用异种骨矿物质进行牙槽嵴保存对种植体周围健康的长期影响:108 例患者的临床和影像学回顾性队列研究。

The long-term impact of alveolar ridge preservation with xenograft bone mineral on peri-implant health after 5 years in function: A retrospective cohort study of 108 patients assessed clinically and radiologically.

机构信息

Centre for Oral Health, School of Health and Welfare, Jönköping University, Jönköping, Sweden.

Department of Periodontology, Institute for Postgraduate Dental Education, Jönköping, Sweden.

出版信息

Clin Exp Dent Res. 2022 Jun;8(3):640-649. doi: 10.1002/cre2.583. Epub 2022 May 5.

Abstract

OBJECTIVES

When teeth are lost, dental implants contribute to improved oral function and quality of life. Limitations in dental implant placement arising from poor bone anatomy may be circumvented via alveolar ridge preservation (ARP). The aim is to evaluate the long-term impact of ARP on peri-implant health and the relationship with common risk indicators such as smoking and history of periodontitis.

MATERIALS AND METHODS

One hundred and eight patients were enrolled in this retrospective cohort study with 308 implants. Of these, ∼41% were placed in bone sites that had previously received ARP with deproteinized bovine bone mineral xenograft. Association between baseline variables: ARP, age, gender, number of implants per patient, anatomical site, smoking, and previous history of grade III/IV periodontitis, and outcome variables: mucositis, peri-implantitis, implant loss, full-mouth plaque score (FMPS), full-mouth bleeding score, and marginal bone loss (MBL) was evaluated using both univariate and multivariate models.

RESULTS

After 5 years, the overall survival rate was 93.7%. The occurrence of peri-implantitis was 21.3% and the extent of MBL was ~2.2 mm. Both peri-implantitis occurrence and MBL were comparable between ARP  and ARP . Smoking is associated with higher FMPS and MBL.

CONCLUSIONS

The findings indicate that peri-implant health can be maintained around dental implants for up to 5 years in ARP  sites using Bio-Oss®. Smoking is a major risk indicator for peri-implantitis, whereas the association between history of periodontitis and the risk of peri-implantitis, based on this specific, well-maintained cohort and the specific implants used, remains inconclusive.

摘要

目的

当牙齿缺失时,种植牙有助于改善口腔功能和生活质量。由于骨解剖结构不良导致的种植牙位置受限,可以通过牙槽嵴保存(ARP)来规避。本研究旨在评估 ARP 对种植体周围健康的长期影响,以及与常见风险指标(如吸烟和牙周炎病史)的关系。

材料和方法

本回顾性队列研究纳入了 108 名患者,共植入了 308 颗种植体。其中约 41%的种植体植入了先前使用脱蛋白牛骨矿物质同种异体移植物进行 ARP 的骨部位。使用单变量和多变量模型评估基线变量(ARP、年龄、性别、每位患者的种植体数量、解剖部位、吸烟和既往 III/IV 级牙周炎病史)和结局变量(黏膜炎、种植体周围炎、种植体丧失、全口菌斑评分、全口出血指数和边缘骨吸收)之间的关系。

结果

5 年后,总体存活率为 93.7%。种植体周围炎的发生率为 21.3%,边缘骨吸收约为 2.2 mm。ARP 和 ARP 位点的种植体周围炎发生和边缘骨吸收程度相当。吸烟与较高的全口菌斑评分和边缘骨吸收相关。

结论

研究结果表明,在使用 Bio-Oss®的 ARP 位点,种植牙周围健康可在 5 年内得到维持。吸烟是种植体周围炎的主要风险指标,而基于该特定、维护良好的队列和使用的特定种植体,牙周炎病史与种植体周围炎风险之间的关系仍不确定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a4/9209797/84fd78ef832e/CRE2-8-640-g002.jpg

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