Hu Bin, Chen Jiarui, Li Wei, Wang Jing, Li Xiaoyan
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Apr;36(4):310-314. doi: 10.13201/j.issn.2096-7993.2022.04.016.
Acquired laryngotracheal stenosis is a laryngeal obstruction disease due to pathologic scar formation. Although acquired laryngotracheal stenosis is hypothesized to be related to fibrosis, its specific mechanisms have yet to be characterized. This article reviews the latest research progress on the mechanisms of laryngotracheal fibrosis, including metabolic changes, immune cell dysregulation, extracellular matrix changes and microbiota.
获得性喉气管狭窄是一种由于病理性瘢痕形成导致的喉梗阻疾病。尽管推测获得性喉气管狭窄与纤维化有关，但其具体机制尚未明确。本文综述了喉气管纤维化机制的最新研究进展，包括代谢变化、免疫细胞失调、细胞外基质变化和微生物群。
