Schreuder A M, Cats B P
Tijdschr Kindergeneeskd. 1987 Feb;55(1):33-8.
A 5 week old preterm boy born by caesarean section on maternal indication at a gestational age of 33 weeks is described, who developed a symptomatic zinc deficiency. He developed diarrhea, dermatological problems and convulsions. IV-zinc supplements and subsequent oral zinc medication induced a complete remission of symptoms. Pathofysiologic sequences as well as disease states (sub-normal intake before and after birth, decreased absorption and increased loss) that can lead to zinc deficiency are discussed. To prevent a deficiency, an intake of 300-450 mcg/kg/day i.v. of elementary zinc in case of total parenteral nutrition and 700 mcg/kg/day p.o. in case of oral feeding is recommended.
本文描述了一名33周胎龄因母亲指征行剖宫产出生的5周大早产男婴，其出现了有症状的锌缺乏。他出现了腹泻、皮肤问题和惊厥。静脉补充锌剂及随后的口服锌药物治疗使症状完全缓解。文中讨论了可导致锌缺乏的病理生理过程以及疾病状态（出生前后摄入不足、吸收减少和丢失增加）。为预防锌缺乏，建议在全胃肠外营养时静脉输注元素锌的摄入量为300 - 450微克/千克/天，口服喂养时口服摄入量为700微克/千克/天。
