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单中心手术后腹壁子宫内膜异位症的累积复发率及复发相关因素。

Cumulative Recurrence Rate and Risk Factors for Recurrent Abdominal Wall Endometriosis after Surgical Treatment in a Single Institution.

机构信息

Department of Obstetrics and Gynecology, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Korea.

Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University School of Medicine, Seoul, Korea.

出版信息

Yonsei Med J. 2022 May;63(5):446-451. doi: 10.3349/ymj.2022.63.5.446.

DOI:10.3349/ymj.2022.63.5.446
PMID:35512747
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9086694/
Abstract

PURPOSE

This study aimed to evaluate the cumulative recurrence rate and risk factors for recurrent abdominal wall endometriosis (AWE) after surgical treatment.

MATERIALS AND METHODS

A retrospective cohort study was conducted at a single gynecological surgery center between January 2004 and December 2020. Patients who were surgically treated and followed up for at least 6 months after surgery were selected.

RESULTS

Eighteen patients with pathologically diagnosed AWE were included in this study. The median follow-up duration was 22.5 months (range, 6-106). The median age was 37 years (range, 22-48), and 33.3% of the patients were nulliparous. Among the patients included in our study, 55.6% complained of a mass with cyclic pain, and 27.8% had a palpable mass. In addition, 22.2% of patients experienced recurrence with 17.5±9.7 months of mean time to recurrence. The cumulative recurrence rates at 24 and 60 months after surgical treatment of AWE were 23.8% and 39.1%, respectively. There were no statistically significant risk factors for the recurrence of AWE, including postoperative medical treatment.

CONCLUSION

The recurrence rate of AWE appears to be correlated with the follow-up duration. There was no statistically significant risk factor for the recurrence of AWE. Unlike ovarian endometriosis, postoperative hormonal treatment does not seem to lower the recurrence of AWE. The findings of the current study may help healthcare providers in counselling and managing patients with AWE.

摘要

目的

本研究旨在评估手术治疗后腹壁子宫内膜异位症(AWE)的累积复发率和复发的相关因素。

材料与方法

本研究为单中心回顾性队列研究,于 2004 年 1 月至 2020 年 12 月在一家妇科手术中心进行。选择接受手术治疗且术后随访至少 6 个月的患者。

结果

本研究共纳入 18 例经病理诊断为 AWE 的患者。中位随访时间为 22.5 个月(范围:6-106 个月)。患者中位年龄为 37 岁(范围:22-48 岁),33.3%为未产妇。纳入本研究的患者中,55.6%主诉有周期性疼痛的肿块,27.8%可触及肿块。此外,22.2%的患者复发,复发时间的平均时间为 17.5±9.7 个月。AWE 手术后 24 个月和 60 个月的累积复发率分别为 23.8%和 39.1%。AWE 复发的相关风险因素,包括术后药物治疗,无统计学意义。

结论

AWE 的复发率似乎与随访时间有关。AWE 复发无统计学意义的风险因素。与卵巢子宫内膜异位症不同,术后激素治疗似乎不会降低 AWE 的复发率。本研究的结果可能有助于为 AWE 患者提供咨询和管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58fb/9086694/3ac2ccc2488d/ymj-63-446-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58fb/9086694/90423e933786/ymj-63-446-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58fb/9086694/3ac2ccc2488d/ymj-63-446-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58fb/9086694/90423e933786/ymj-63-446-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58fb/9086694/3ac2ccc2488d/ymj-63-446-g002.jpg

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Eur J Obstet Gynecol Reprod Biol. 2020 Sep;252:225-227. doi: 10.1016/j.ejogrb.2020.06.054. Epub 2020 Jun 26.
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Am J Transl Res. 2022 Nov 15;14(11):7924-7931. eCollection 2022.
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J Clin Med. 2020 Jan 6;9(1):154. doi: 10.3390/jcm9010154.
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