Division of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8052, St Louis, MO 63110, USA.
Toronto Lung Transplant Program, Division of Thoracic Surgery, Department of Surgery, University Health Network, University of Toronto, Toronto General Hospital, 200 Elizabeth Street, 9N969, Toronto, Ontario M5G 2C4, Canada.
Thorac Surg Clin. 2022 May;32(2):167-174. doi: 10.1016/j.thorsurg.2021.11.003.
An increased focus on improving efficiency and decreasing costs has resulted in alternative models of donor management and organ recovery. The specialized donor care facility model provides highly efficient and cost-effective donor care at a free-standing facility, resulting in improved organ yield, shorter ischemic times, decreased travel, and fewer nighttime operations. Ex vivo lung perfusion (EVLP) improves utilization of extended criteria donor lungs, and centralized EVLP facilities have the potential to increase transplant volumes for smaller transplant programs in specified geographic regions. These alternative models are increasingly being used in the United States to improve waitlist mortality and combat the ongoing donor organ shortage.
对提高效率和降低成本的日益关注导致了供体管理和器官回收的替代模式。专门的供体护理设施模式在独立的设施中提供高效和具有成本效益的供体护理，从而提高了器官的产量，缩短了缺血时间，减少了旅行，并减少了夜间手术。离体肺灌注（EVLP）提高了扩展标准供体肺的利用率，集中的 EVLP 设施有可能增加特定地理区域较小移植项目的移植量。这些替代模式在美国越来越多地被用于降低等待名单死亡率和解决持续存在的供体器官短缺问题。
