Departments of Clinical and Health Psychology.
Pain Research Center of Excellence.
Clin J Pain. 2022 Jul 1;38(7):470-475. doi: 10.1097/AJP.0000000000001042.
Chronic pain, cognitive deficits, and pain-related disability are interrelated. The prevalence of chronic pain and undiagnosed cognitive difficulties in middle age and older adults is increasing. Of the cognitive systems, executive function and episodic memory are most relevant to chronic pain. We examined the hypothesis that cognitive screening composite scores for executive function and memory would negatively associate with pain intensity and pain disability in a group of middle-aged and older adults with knee pain with or at risk for osteoarthritis.
A total of 120 adults (44 men/76 women), an average age of 59 years, participated in the study. Demographic, health history, clinical pain, and cognitive measures were completed. Relationships between pain intensity, pain disability, and the Montreal Cognitive Assessment (MoCA) total and composite scores were examined with relevant covariates in the model.
MoCA raw scores ranged from 13 to 30 with a mean score of 23.9. Pain intensity was negatively associated with overall MoCA total and executive function and memory composite scores. Pain disability over the previous 6 months was negatively associated with executive function, while pain disability over the past 48 hours was not associated with executive function.
The results of the current study demonstrates associations between pain metrics and cognitive domain scores within a common cognitive screening tool.
慢性疼痛、认知障碍和与疼痛相关的残疾相互关联。中年和老年人慢性疼痛和未确诊的认知困难的患病率正在增加。在认知系统中,执行功能和情景记忆与慢性疼痛最相关。我们假设在一组患有或有膝关节骨关节炎风险的中年和老年人中,认知功能的执行功能和记忆综合评分与疼痛强度和疼痛残疾呈负相关。
共有 120 名成年人(44 名男性/76 名女性),平均年龄 59 岁,参与了这项研究。完成了人口统计学、健康史、临床疼痛和认知测量。在模型中,用相关协变量来检验疼痛强度、疼痛残疾与蒙特利尔认知评估(MoCA)总分和综合评分之间的关系。
MoCA 原始分数范围为 13 至 30,平均分数为 23.9。疼痛强度与整体 MoCA 总分和执行功能及记忆综合评分呈负相关。过去 6 个月的疼痛残疾与执行功能呈负相关,而过去 48 小时的疼痛残疾与执行功能无关。
目前的研究结果表明,在一个常见的认知筛查工具中,疼痛指标与认知域评分之间存在关联。