One pot fabrication of fluorescein functionalized manganese dioxide for fluorescence "Turn OFF-ON" sensing of hydrogen peroxide in water and cosmetic samples.

In recent decades, HO has been promoted as a health indicator because its moderate to high levels can cause some health problems. Herein, we developed a new fluorescent nanoprobe for rapid, selective and sensitive detection of HO. The fluorescent nanoprobe is composed of fluorescein dye (FLS) as a fluorescent probe and MnO nanosheets (MnO NS) as a quencher. In this study, HO can reduce MnO NS in the synthesized composite and release FLS, causing sufficient recovery of fluorescent signal related to the concentration of HO. The nanoprobe, with / at 495/515 nm, has a linear range of 0.04-30 μM, with a limit of detection (LOD) of 7.5 nM and a limit of quantitation (LOQ) of 21 nM. The mean relative standard deviation (RSD) was 2.6% and the applicability of the method was demonstrated by the determination of HO in water and cosmetic samples.