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伊德里斯萨·普耶综合医院(HOGIP)泌尿外科膀胱血吸虫瘤的流行病学和诊断方面

Epidemiological and Diagnostic Aspects of Bladder Bilharziomas in the Urology Department of Idrissa Pouye General Hospital (HOGIP).

作者信息

Gaye Oumar, Jalloh Mohamed, Thiam Ngor M, Ndoye Medina, Dansokho Khadidiatou, Bellamine Youssef, Kouka Saint C N, Dial Cherif, Mbodji Mouhamadou M, Cassell Ayun, Labou Issa, Niang Lamine, Gueye Serigne

机构信息

Urology-andrology Department, Hôpital General Idrissa Pouye, Dakar, Senegal.

Pathological Anatomy Laboratory, Hôpital General Idrissa Pouye, Dakar, Senegal.

出版信息

Adv Urol. 2021 Mar 25;2021:4536381. doi: 10.1155/2021/4536381. eCollection 2021.

Abstract

OBJECTIVE

The aim of our study is to assess the diagnostic aspects of bladder bilharzioma in the Urology Department of Idrissa Pouye General Hospital (Senegal).

MATERIALS AND METHODS

It is a descriptive study from January 2013 to December 2018. The patients included in the study were those who had anatomopathological examination of bladder biopsy that showed a schistosomiasis pseudotumor of the bladder. The variables studied were sociodemographic, clinical symptoms, imaging findings, histology, and treatment. The data have been saved and analyzed by the 2013 Excel software.

RESULTS

Thirteen patients were included in our study. The average age was 27 ± 12.1 years. Sex ratio was 1.6. The majority of the patients were from the northern part of Senegal. Hematuria was the main symptom for all the patients. Cystoscopy was performed for all the patients and showed 5 granulomas and 8 fibrocalcic polyps. A transurethral resection of the bladder was performed, and treatment with praziquantel (40 mg/kg of bodyweight) has been carried out. One patient presented precancerous lesions such as metaplasia and dysplasia of the bladder mucosa. After a median follow-up of 40 months (6-57 months), ten patients had a favorable clinical and endoscopic outcome.

CONCLUSION

Granulomas and fibrocalcic polyps of the bladder mucosa are, respectively, confused with squamous cell carcinoma and bladder lithiasis in endemic areas of schistosomiasis. Good cystoscopy interpretation can provide the diagnosis of bladder bilharzioma and start the treatment.

摘要

目的

我们研究的目的是评估伊德里斯萨·普耶综合医院(塞内加尔)泌尿外科膀胱血吸虫瘤的诊断情况。

材料与方法

这是一项2013年1月至2018年12月的描述性研究。纳入研究的患者为膀胱活检经解剖病理学检查显示为膀胱血吸虫病假瘤的患者。所研究的变量包括社会人口统计学、临床症状、影像学检查结果、组织学和治疗情况。数据已通过2013版Excel软件保存并分析。

结果

我们的研究纳入了13例患者。平均年龄为27±12.1岁。性别比为1.6。大多数患者来自塞内加尔北部。血尿是所有患者的主要症状。所有患者均接受了膀胱镜检查,发现5个肉芽肿和8个纤维钙化性息肉。对所有患者进行了经尿道膀胱切除术,并使用吡喹酮(40mg/kg体重)进行治疗。1例患者出现癌前病变,如膀胱黏膜化生和发育异常。中位随访40个月(6 - 57个月)后,10例患者临床和内镜检查结果良好。

结论

在血吸虫病流行地区,膀胱黏膜肉芽肿和纤维钙化性息肉分别易与鳞状细胞癌和膀胱结石相混淆。良好的膀胱镜检查解读可实现膀胱血吸虫瘤的诊断并启动治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6ad/9066376/db4e6ee43082/AU2021-4536381.001.jpg

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