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新生杂交猪的先天性肢体畸形

Congenital Limb Deformities in a Neonatal Crossbred Pig.

作者信息

Rahe Michael C, Evrard Laurence, Holmes Neil B

机构信息

Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA.

VetCT, St John's Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK.

出版信息

Case Rep Vet Med. 2022 Apr 26;2022:5516633. doi: 10.1155/2022/5516633. eCollection 2022.

Abstract

PURPOSE

To describe the pathology and imaging findings in two neonatal piglets with congenital limb deformities.

METHODS

The litter from a second parity crossbred sow presented with four mummified fetuses, three stillborn piglets, and two live piglets with notable limb deformities that were unable to effectively ambulate. The piglets were euthanized and submitted for gross and histological evaluation.

RESULTS

Both pigs had bilateral secondary cleft palates, with hypoplasia of the nasal turbinates, and external rotation of the forelimbs. One pig displayed bilateral cryptorchidism, markedly thin and shortened hindlimbs, and syndactyly of both hind feet. Radiographs and gross dissection confirmed the presence of single ossified proximal to distal phalanges of both feet, bilaterally shortened tibias with fibular aplasia, and delayed ossification of tarsal as well as carpal bones.

CONCLUSIONS

To the author's knowledge, this is the first reported case of hindlimb meromelia with syndactyly in a pig.

摘要

目的

描述两只患有先天性肢体畸形的新生仔猪的病理学和影像学表现。

方法

一头经产杂交母猪所产的一窝仔猪中有四头木乃伊化胎儿、三头死产仔猪以及两头患有明显肢体畸形且无法有效行走的存活仔猪。对这些仔猪实施安乐死后进行大体和组织学评估。

结果

两头猪均有双侧继发性腭裂、鼻甲发育不全以及前肢外旋。其中一头猪表现为双侧隐睾、后肢明显细短以及双后足并指(趾)畸形。X线片和大体解剖证实,双脚均存在从近端指(趾)骨到远端指(趾)骨的单一骨化、双侧胫骨缩短且腓骨发育不全,以及跗骨和腕骨骨化延迟。

结论

据作者所知,这是首次报道猪出现后肢短肢畸形并伴有并指(趾)畸形的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bd2/9064526/f555189fc420/CRIVEM2022-5516633.001.jpg

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