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Activation of c-ras oncogenes by mutations and amplification.

作者信息

Sistonen L, Alitalo K

出版信息

Ann Clin Res. 1986;18(5-6):297-303.

PMID:3551775
Abstract

About 15% of all human tumours, including carcinomas, sarcomas, melanomas and leukaemias, contain c-ras oncogenes, which can be detected by a variety of methods. The activating lesion in the c-ras oncogenes is most often a point mutation affecting certain critical amino acid residues of its protein product. The clinical significance of c-ras oncogenes is not yet clear.

摘要

相似文献

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Activation of c-ras oncogenes by mutations and amplification.
Ann Clin Res. 1986;18(5-6):297-303.
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