对尿路致病性细菌对甲氧苄啶-磺胺甲恶唑及其他抗菌药物敏感性变化模式的五年调查。
Five-year survey of changing patterns of susceptibility of bacterial uropathogens to trimethoprim-sulfamethoxazole and other antimicrobial agents.
作者信息
Alon U, Davidai G, Berant M, Merzbach D
出版信息
Antimicrob Agents Chemother. 1987 Jan;31(1):126-8. doi: 10.1128/AAC.31.1.126.
Abstract
We analyzed the antibiotic susceptibility of 5,348 urinary isolates of Escherichia coli, "Klebsiella aerogenes," and Proteus mirabilis grown in three laboratories from 1980 to 1985. A continuous rise in resistance to trimethoprim-sulfamethoxazole was observed; 63% of the strains from inpatients in 1984 and 51% of those from outpatients in 1985 were resistant to this drug. Isolates from outpatients in 1985 were mostly susceptible to nitrofurantoin (mean susceptibility, 92%) and to oral cephalosporins (mean susceptibility, 84%). As for isolates from inpatients, none of the antimicrobial agents now used was satisfactory for initial chemotherapy, indicating a need for new antibacterial strategies.
摘要
我们分析了1980年至1985年在三个实验室培养的5348株大肠埃希菌、产气克雷伯菌和奇异变形杆菌的尿液分离株的抗生素敏感性。观察到对甲氧苄啶-磺胺甲恶唑的耐药性持续上升；1984年住院患者的菌株中有63%以及1985年门诊患者的菌株中有51%对该药物耐药。1985年门诊患者的分离株大多对呋喃妥因敏感（平均敏感性为92%）和口服头孢菌素敏感（平均敏感性为84%）。至于住院患者的分离株，目前使用的抗菌药物中没有一种对初始化疗令人满意，这表明需要新的抗菌策略。
相似文献
1
Five-year survey of changing patterns of susceptibility of bacterial uropathogens to trimethoprim-sulfamethoxazole and other antimicrobial agents.
Antimicrob Agents Chemother. 1987 Jan;31(1):126-8. doi: 10.1128/AAC.31.1.126.
2
Trimethoprim/sulphamethoxazole resistance in Escherichia coli and Klebsiella spp. urinary isolates.
Afr J Med Med Sci. 1988 Sep;17(3):175-9.
3
[Bacteriological studies in outpatients with acute urinary tract infections with particular reference to the resistance spectrum (author's transl)].
Infection. 1976;4(2):11-15. doi: 10.1007/BF01638341.
4
[Resistance patterns of certain Enterobacteriaceae in hospital and outpatients, with particular reference to trimethoprim-sulfamethoxazole (author's transl)].
MMW Munch Med Wochenschr. 1976 Feb 27;118(9):275-8.
5
Technique for determining the bactericidal effect of drug combinations.
Antimicrob Agents Chemother. 1974 Jun;5(6):630-3. doi: 10.1128/AAC.5.6.630.
6
A Canadian national surveillance study of urinary tract isolates from outpatients: comparison of the activities of trimethoprim-sulfamethoxazole, ampicillin, mecillinam, nitrofurantoin, and ciprofloxacin. The Canadian Urinary Isolate Study Group.
Antimicrob Agents Chemother. 2000 Apr;44(4):1089-92. doi: 10.1128/AAC.44.4.1089-1092.2000.
7
Resistance of urinary tract isolates of Escherichia coli to trimethoprim, cotrimoxazole and ampicillin.
N Z Med J. 1988 Apr 27;101(844):216-7.
8
[Evolution from 1976 to 1986 of bacterial prevalence and sensitivity to urinary antibiotics of bacteria isolated from urine cultures at a city microbiology laboratory].
Pathol Biol (Paris). 1988 May;36(5):439-41.
9
Mecillinam activity compared to ampicillin, trimethoprim/sulfamethoxazole, ciprofloxacin and nitrofurantoin against urinary tract isolates of gram-negative bacilli.
Chemotherapy. 1998 Nov-Dec;44(6):391-6. doi: 10.1159/000007149.
10
Urinary tract infections in South Croatia: aetiology and antimicrobial resistance.
Int J Antimicrob Agents. 2003 Oct;22 Suppl 2:61-4. doi: 10.1016/s0924-8579(03)00233-4.
引用本文的文献
1
Antibiotic resistance in bacterial urinary tract infections, 1991 to 1997.
West J Med. 1998 Nov;169(5):265-8.
2
Evaluation of use of a new chromogenic agar in detection of urinary tract pathogens.
J Clin Microbiol. 1998 Apr;36(4):990-4. doi: 10.1128/JCM.36.4.990-994.1998.
3
Risk factors for fecal colonization with trimethoprim-resistant and multiresistant Escherichia coli among children in day-care centers in Houston, Texas.
Antimicrob Agents Chemother. 1990 Jul;34(7):1429-34. doi: 10.1128/AAC.34.7.1429.
本文引用的文献
1
Trimethoprim resistance in Finland after five years' use of plain trimethoprim.
Br Med J. 1980 Jan 12;280(6207):72-4. doi: 10.1136/bmj.280.6207.72.
2
Trimethoprim-sulfamethoxazole: an assessment of more than 12 years of use.
Rev Infect Dis. 1982 Mar-Apr;4(2):196-236. doi: 10.1093/clinids/4.2.196.
3
Amoxicillin-clavulanic acid in treatment of urinary tract infection due to gram-negative bacteria resistant to penicillin.
Antimicrob Agents Chemother. 1981 Dec;20(6):800-2. doi: 10.1128/AAC.20.6.800.
4
Emergence of high-level trimethoprim resistance in fecal Escherichia coli during oral administration of trimethoprim or trimethoprim--sulfamethoxazole.
N Engl J Med. 1982 Jan 21;306(3):130-5. doi: 10.1056/NEJM198201213060302.
5
Trimethoprim-sulfamethoxazole.
N Engl J Med. 1980 Aug 21;303(8):426-32. doi: 10.1056/NEJM198008213030804.
6
The use of trimethoprim-sulfamethoxazole in children: a review of adverse reactions and indications.
Pediatr Infect Dis. 1984 Jul-Aug;3(4):349-57. doi: 10.1097/00006454-198407000-00018.
7
Augmentin (amoxycillin-clavulanic acid) compared with co-trimoxazole in urinary tract infections.
Br Med J (Clin Res Ed). 1984 Jul 14;289(6437):82-3. doi: 10.1136/bmj.289.6437.82.
8
Mechanism of action of trimethoprim-sulfamethoxazole. I.
J Infect Dis. 1973 Nov;128:Suppl:433-6 p. doi: 10.1093/infdis/128.supplement_3.s433.
9
Mechanism of action of trimethoprim-sulfamethoxazole. II.
J Infect Dis. 1973 Nov;128:Suppl: 437-41. doi: 10.1093/infdis/128.supplement_3.s437.
10
Trimethoprim resistance determined by R factors.
Br Med J. 1972 Mar 18;1(5802):726-8. doi: 10.1136/bmj.1.5802.726.
Zotero 插件