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具有无细胞合成生物系统的便携式环境信号检测生物传感器。

Portable environment-signal detection biosensors with cell-free synthetic biosystems.

作者信息

Lin Xiaomei, Li Yuting, Li Zhixia, Hua Rui, Xing Yuyang, Lu Yuan

机构信息

Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University Beijing 100084 China

出版信息

RSC Adv. 2020 Oct 26;10(64):39261-39265. doi: 10.1039/d0ra05293k. eCollection 2020 Oct 21.

Abstract

By embedding regulated genetic circuits and cell-free systems onto a paper, the portable biosensing platform showed the possibility of detecting environmental pollutants, namely arsenic ions and bacterial quorum-sensing signal AHLs (-acyl homoserine lactones). This platform has a great potential for practical environmental management and diagnosis.

摘要

通过将调控基因电路和无细胞系统嵌入纸张中,这种便携式生物传感平台显示出检测环境污染物的可能性,即砷离子和细菌群体感应信号AHLs(酰基高丝氨酸内酯)。该平台在实际环境管理和诊断方面具有巨大潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cecb/9057330/66482a1c4743/d0ra05293k-f1.jpg

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