银催化（杂）芳烃的区域选择性氘代反应以及2-烷基氮杂芳烃的α-氘代反应。
Silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes.
作者信息
Dong Baobiao, Cong Xuefeng, Hao Na
机构信息
Department of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University Luzhou 646000 China
Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University Changchun 130024 China
出版信息
RSC Adv. 2020 Jul 6;10(43):25475-25479. doi: 10.1039/d0ra02358b. eCollection 2020 Jul 3.
A simple silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes has been described. This strategy provides an efficient and practical avenue to access various deuterated electron-rich arenes, azaarenes and α-deuterated 2-alkyl azaarenes with good to excellent deuterium incorporation utilizing DO as the source of deuterium atoms.
已报道了一种简单的银催化（杂）芳烃区域选择性氘代及2-烷基氮杂芳烃α-氘代反应。该策略提供了一条高效实用的途径，以DO作为氘原子源，可获得各种氘代富电子芳烃、氮杂芳烃以及具有良好至优异氘掺入率的α-氘代2-烷基氮杂芳烃。
Zotero 插件