Li Shuaihui, Ma Yashen, Liu Yongkang, Xin Gu, Wang Minghua, Zhang Zhihong, Liu Zhongyi
School of Chemical Engineering and Energy, Zhengzhou University No. 100 Science Avenue Zhengzhou 450001 Henan China
Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry Zhengzhou 450002 China.
RSC Adv. 2019 Jan 23;9(6):2997-3003. doi: 10.1039/c8ra09511f. eCollection 2019 Jan 22.
A three dimensional (3D) nanostructured composite based on the self-assembly of MoS nanospheres and polyaniline (PANI) loaded on reduced graphene oxide (denoted by 3D MoS-PANI/rGO) was prepared a feasible one-pot hydrothermal process. The 3D MoS-PANI/rGO nanocomposite not only exhibits good functionality and bioaffinity but also displays high electrochemical catalytic activity. As such, the developed 3D MoS-PANI/rGO nanocomposite can be employed as the sensing platform for simultaneously detecting small biomolecules, , ascorbic acid (AA), dopamine (DA), and uric acid (UA). The peak currents obtained from the differential pulse voltammetry (DPV) measurements depended linearly on the concentrations in the wide range from 50 μM to 8.0 mM, 5.0 to 500 μM, and 1.0 to 500 μM, giving low detection limits of 22.20, 0.70, and 0.36 μM for AA, DA, and UA, respectively. Furthermore, the 3D MoS-PANI/rGO-based electrochemical sensor also exhibited high selectivity, good reproducibility and stability toward small molecule detection. The present sensing strategy based on 3D MoS-PANI/rGO suggests a good reliability in the trace determination of electroactive biomolecules.
通过一种可行的一锅水热法制备了一种基于负载在还原氧化石墨烯上的二硫化钼（MoS）纳米球和聚苯胺（PANI）自组装的三维（3D）纳米结构复合材料（表示为3D MoS-PANI/rGO）。3D MoS-PANI/rGO纳米复合材料不仅具有良好的功能和生物亲和性，还表现出高电化学催化活性。因此，所开发的3D MoS-PANI/rGO纳米复合材料可作为同时检测小分子生物分子（如抗坏血酸（AA）、多巴胺（DA）和尿酸（UA））的传感平台。从差分脉冲伏安法（DPV）测量中获得的峰值电流在50 μM至8.0 mM、5.0至500 μM和1.0至500 μM的宽范围内与浓度呈线性关系，AA、DA和UA的检测限分别低至22.20、0.70和0.36 μM。此外，基于3D MoS-PANI/rGO的电化学传感器在小分子检测方面还表现出高选择性、良好的重现性和稳定性。基于3D MoS-PANI/rGO的当前传感策略在电活性生物分子的痕量测定中显示出良好的可靠性。
