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有效种子辅助合成锚定氮掺杂石墨烯的金纳米粒子用于电化学检测葡萄糖和多巴胺。

Effective seed-assisted synthesis of gold nanoparticles anchored nitrogen-doped graphene for electrochemical detection of glucose and dopamine.

机构信息

Advanced Materials Institute of BIN Convergence Technology (BK21 plus Global) & Dept. of BIN Convergence Technology, Chonbuk National University, Jeonju, Jeonbuk 54896, Republic of Korea.

Advanced Materials Institute of BIN Convergence Technology (BK21 plus Global) & Dept. of BIN Convergence Technology, Chonbuk National University, Jeonju, Jeonbuk 54896, Republic of Korea; Carbon Composite Research Centre, Department of Polymer & Nanoscience and Technology, Chonbuk National University, Jeonju, Jeonbuk 54896, Republic of Korea.

出版信息

Biosens Bioelectron. 2016 Jul 15;81:259-267. doi: 10.1016/j.bios.2016.02.070. Epub 2016 Mar 2.

Abstract

A novel gold nanoparticle-anchored nitrogen-doped graphene (AuNP/NG) nanohybrid was synthesized through a seed-assisted growth method, as an effective electrocatalyst for glucose and dopamine detection. The AuNP/NG nanohybrids exhibited high sensitivity and selectivity toward glucose and dopamine sensing applications. The as-synthesized nanohybrids exhibited excellent catalytic activity toward glucose, with a linear response throughout the concentration range from 40μM to 16.1mM, a detection limit of 12μM, and a short response time (∼ 10s). It also exhibited an excellent response toward DA, with a wide detection range from 30nM to 48μM, a low detection limit of 10nM, and a short response time (∼ 8s). Furthermore, it also showed long-term stability and high selectivity for the target analytes. These results imply that such nanohybrids show a great potential for electrochemical biosensing application.

摘要

通过种子辅助生长法合成了一种新型的金纳米粒子锚定氮掺杂石墨烯(AuNP/NG)纳米杂化物,作为葡萄糖和多巴胺检测的有效电催化剂。AuNP/NG 纳米杂化物在葡萄糖和多巴胺传感应用中表现出高灵敏度和选择性。所合成的纳米杂化物对葡萄糖表现出优异的催化活性,在 40μM 至 16.1mM 的浓度范围内具有线性响应,检测限为 12μM,响应时间短(约 10s)。它对 DA 也表现出优异的响应,检测范围从 30nM 到 48μM,检测限低至 10nM,响应时间短(约 8s)。此外,它对目标分析物还表现出长期稳定性和高选择性。这些结果表明,这种纳米杂化物在电化学生物传感应用中具有很大的潜力。

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