Nauman Muhammad, Alnasir Muhammad Hisham, Hamayun Muhammad Asif, Wang YiXu, Shatruk Michael, Manzoor Sadia
Department of Physics, Kyungpook National University Daegu 41566 Korea
Department of Physics, COMSATS University Islamabad 45550 Pakistan
RSC Adv. 2020 Jul 29;10(47):28383-28389. doi: 10.1039/d0ra05394e. eCollection 2020 Jul 27.
Gadolinium silicide (GdSi) nanoparticles are an interesting class of materials due to their high magnetization, low Curie temperature, low toxicity in biological environments and their multifunctional properties. We report the magnetic and magnetothermal properties of gadolinium silicide (GdSi) nanoparticles prepared by surfactant-assisted ball milling of arc melted bulk ingots of the compound. Using different milling times and speeds, a wide range of crystallite sizes (13-43 nm) could be produced and a reduction in Curie temperature ( ) from 340 K to 317 K was achieved, making these nanoparticles suitable for self-controlled magnetic hyperthermia applications. The magnetothermal effect was measured in applied AC magnetic fields of amplitude 164-239 Oe and frequencies 163-519 kHz. All particles showed magnetic heating with a strong dependence of the specific absorption rate (SAR) on the average crystallite size. The highest SAR of 3.7 W g was measured for 43 nm sized nanoparticles of GdSi. The high SAR and low , (within the therapeutic range for magnetothermal therapy) makes the GdSi behave like self-regulating heat switches that would be suitable for self-controlled magnetic hyperthermia applications after biocompatibility and cytotoxicity tests.
硅化钆（GdSi）纳米颗粒是一类有趣的材料，因为它们具有高磁化强度、低居里温度、在生物环境中的低毒性以及多功能特性。我们报告了通过表面活性剂辅助球磨该化合物的电弧熔炼块状锭体制备的硅化钆（GdSi）纳米颗粒的磁性和磁热性能。使用不同的球磨时间和速度，可以产生广泛的微晶尺寸（13 - 43纳米），并且居里温度（ ）从340 K降低到317 K，使得这些纳米颗粒适用于自控磁热疗应用。在幅度为164 - 239 Oe、频率为163 - 519 kHz的外加交流磁场中测量了磁热效应。所有颗粒都表现出磁热效应，比吸收率（SAR）强烈依赖于平均微晶尺寸。对于43纳米尺寸的GdSi纳米颗粒，测量到的最高SAR为3.7 W g 。高SAR和低 （在磁热疗的治疗范围内）使得GdSi表现得像自调节热开关，在进行生物相容性和细胞毒性测试后，将适用于自控磁热疗应用。
