Seraj Sanaz, Rouhani Shohre, Faridbod Farnoush
Department of Organic Colorants, Institute for Color Science and Technology Tehran Iran
Center of Excellence for Color Science and Technology (CECST), Institute for Color Science and Technology Tehran Iran.
RSC Adv. 2019 Jun 7;9(31):17933-17940. doi: 10.1039/c9ra01757g. eCollection 2019 Jun 4.
A highly selective and sensitive fluorescent sensor for the determination of fructose is developed. The fluorescent sensor was prepared by incorporating a new naphthalimide dye with a planar structure as a selectophore and graphene oxide (GO) nanoplatelets as a quencher for rapid optical detection of fructose. The designed probe, made with the high fusion loop-containing dye, along with the GO nanoplatelets, detected fructose over the other monosaccharides very well. The proposed sensor displays a linear response range of 7 × 10 to 3 × 10 M with a low limit of detection of 23 × 10 M in solution at pH 7.4. This sensor shows a good selectivity towards fructose with respect to other saccharides. The proposed sensor was then applied to the determination of fructose in human plasma with satisfactory results.
开发了一种用于测定果糖的高选择性和灵敏的荧光传感器。该荧光传感器是通过将一种具有平面结构的新型萘酰亚胺染料作为选择体与氧化石墨烯（GO）纳米片作为猝灭剂相结合来制备的，用于果糖的快速光学检测。用含高融合环的染料与GO纳米片制成的设计探针能很好地检测果糖，而不是其他单糖。所提出的传感器在pH 7.4的溶液中显示出7×10至3×10 M的线性响应范围，检测下限低至23×10 M。该传感器对果糖相对于其他糖类具有良好的选择性。然后将所提出的传感器应用于人体血浆中果糖的测定，结果令人满意。
