Wu Shuanggen, Li Fenfang, Zeng Liangbin, Wang Chaoyun, Yang Yuanru, Tan Zhijian
College of Chemistry and Chemical Engineering, Central South University Changsha 410083 China.
Institute of Bast Fiber Crops, Center of Southern Economic Crops, Chinese Academy of Agricultural Sciences Changsha 410205 China
RSC Adv. 2019 Apr 1;9(18):10100-10108. doi: 10.1039/c8ra06929h. eCollection 2019 Mar 28.
Amino acid-based ionic liquids (AAILs) are generally thought of as green solvents and widely used in many regions without systematic assessment of their effect on the environment or human health. In this work, a series of AAILs with different cations and amino acid anions were prepared and characterized, after which their microbial toxicity, phytotoxicity, and biodegradability were evaluated. The results showed that not all AAILs had low toxicity against microorganisms and that some AAILs were highly toxic towards the targeted microorganisms. The phytotoxic effect of the AAILs on rice ( L.) further demonstrated that AAILs should not be presumed to be non-toxic to plants. Moreover, the biodegradability tests showed that majority of AAILs were not satisfactorily biodegradable. In summary, not all AAILs are non-toxic or biodegradable, and their effect on the environment and human health must be assessed before their mass preparation and application.
基于氨基酸的离子液体（AAILs）通常被认为是绿色溶剂，并在许多地区广泛使用，却未对其对环境或人类健康的影响进行系统评估。在这项工作中，制备并表征了一系列具有不同阳离子和氨基酸阴离子的AAILs，之后评估了它们的微生物毒性、植物毒性和生物降解性。结果表明，并非所有AAILs对微生物都具有低毒性，一些AAILs对目标微生物具有高毒性。AAILs对水稻的植物毒性进一步表明，不应假定AAILs对植物无毒。此外，生物降解性测试表明，大多数AAILs的生物降解性并不理想。总之，并非所有AAILs都是无毒或可生物降解的，在大规模制备和应用之前，必须评估它们对环境和人类健康的影响。
