Slepecky N, Chamberlain S C
Cell Tissue Res. 1987 Apr;248(1):63-6. doi: 10.1007/BF01239963.
The distribution of tropomyosin, actin and tubulin in the supporting cells of the organ of Corti was studied by immunofluorescent localization of antibodies to these proteins. Tropomyosin colocalizes with actin and tubulin in the regions of the tunnel pillar and Deiters cells where actin microfilaments and microtubules had previously been observed ultrastructurally. Despite the implications of the presence of antiparallel actin filaments in the supporting cells, the presence of tropomyosin and the absence of myosin suggest that the role of tropomyosin may be to confer rigidity to the actin filaments. Thus the primary function of the cytoskeletal proteins in the supporting cells may be structural.
通过对这些蛋白质抗体进行免疫荧光定位，研究了原肌球蛋白、肌动蛋白和微管蛋白在柯蒂氏器支持细胞中的分布。原肌球蛋白在隧道柱和Dieters细胞区域与肌动蛋白和微管蛋白共定位，在这些区域先前已通过超微结构观察到肌动蛋白微丝和微管。尽管支持细胞中存在反平行肌动蛋白丝，但原肌球蛋白的存在和肌球蛋白的缺失表明，原肌球蛋白的作用可能是赋予肌动蛋白丝刚性。因此，支持细胞中细胞骨架蛋白的主要功能可能是结构性的。
