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关节内注射肉毒毒素 A 对颞下颌关节紊乱症状的影响。

The effect of intraarticular botulinum toxin-A injection on symptoms of temporomandibular joint disorder.

机构信息

Department of Oral and Maxillofacial Surgery, Istanbul Medipol University Faculty of Dentistry, Istanbul, Turkey.

Department of Oral and Maxillofacial Surgery, Istanbul Medipol University Faculty of Dentistry, Istanbul, Turkey.

出版信息

J Stomatol Oral Maxillofac Surg. 2022 Oct;123(5):e316-e320. doi: 10.1016/j.jormas.2022.04.019. Epub 2022 May 14.

Abstract

INTRODUCTION

Application of arthrocentesis in temporomandibular joint disorders preferred and suggested therapeutic treatment option in recent years. This study was designed to investigate and compare the effect of intra-articular injection of botulinum toxin-A (Btx-A) on pain and mouth opening after arthrocentesis in nonreduction disc displacement.

MATERIALS AND METHODS

This restrospective study was conducted on 30 patients with a visual analogue scale is higher than five and limited mouth opening. Patients were divided into 2 groups as conventional arthrocentesis group (group A) and intra-articular Btx-A injection following arthrocentesis group (group B). Maximum mouth openining and temporomandibular joint pain were measured in preoperative (t0) and at postoperative 1-week (t1), 1-month (t2) and 6-month (t3).

RESULTS

When VAS scores of group A and group B were examined, no statistical difference was observed at t0 and t1 time intervals; an increased in mouth opening values and decreased VAS score values were observed in both groups in the 1 month (t2) and 6t3) months, mostly in group A.

CONCLUSION

İntra-articular injection of Btx-A following arthrocentesis can induce mouth opening and reduce the pain and dysfunction in patients with anterior disc displacement.

摘要

简介

近年来,关节穿刺术已成为治疗颞下颌关节紊乱的首选方法。本研究旨在探讨和比较关节内注射肉毒毒素 A(Btx-A)对不可复性盘前移位患者关节穿刺术后疼痛和张口度的影响。

材料和方法

本回顾性研究纳入了 30 名视觉模拟评分高于 5 分且张口受限的患者。患者分为常规关节穿刺术组(A 组)和关节穿刺术后关节内注射 Btx-A 组(B 组)。术前(t0)、术后 1 周(t1)、1 个月(t2)和 6 个月(t3)测量最大张口度和颞下颌关节疼痛。

结果

在 t0 和 t1 时间点,A 组和 B 组的 VAS 评分无统计学差异;两组在 1 个月(t2)和 6 个月(t3)时,张口度增加,VAS 评分降低,A 组更为明显。

结论

关节内注射 Btx-A 可增加张口度,减轻不可复性盘前移位患者的疼痛和功能障碍。

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