Obstetrics and Gynecology, Division of Gynecologic Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Obstetrics and Gynecology, Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois, USA.
Int J Gynecol Cancer. 2022 Jul 4;32(7):931-938. doi: 10.1136/ijgc-2022-003476.
For patients diagnosed with ovarian, uterine, or cervical cancer, race impacts expected outcome, with black women suffering worse survival than white women for all three malignancies. Moreover, outcomes for black women have largely worsened since the 1970s. In this narrative review, we first provide an updated summary of the incidence and survival of ovarian, uterine, and cervical cancer, with attention paid to differences between white and black patients. We then offer a theoretical framework detailing how racial disparities in outcomes for each of the gynecologic malignancies can be explained as the sum result of smaller white-black differences in experience of preventive strategies, implementation of screening efforts, early detection of symptomatic disease, and appropriate treatment. Much research has been published regarding racial disparities in each of these domains, and with this review, we seek to curate the relevant literature and present an updated understanding of disparities between black and white women with gynecologic malignancies.
对于被诊断患有卵巢癌、子宫癌或宫颈癌的患者，种族会影响预期结果，黑人女性在这三种癌症的存活率都比白人女性差。此外，自 20 世纪 70 年代以来，黑人女性的预后情况在很大程度上恶化了。在这篇叙述性综述中，我们首先提供了卵巢癌、子宫癌和宫颈癌发病率和生存率的最新总结，重点关注白人和黑人患者之间的差异。然后，我们提供了一个理论框架，详细说明了为什么妇科恶性肿瘤的结果在每个种族之间存在差异，可以解释为白人-黑人在预防策略的体验、筛查工作的实施、症状性疾病的早期发现和适当治疗方面的差异较小。关于这些领域中的每一个领域都已经发表了大量的研究，通过本综述，我们试图整理相关文献，并对妇科恶性肿瘤中黑人和白人女性之间的差异有一个最新的认识。
