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分子乳腺成像的最新进展。

Updates in Molecular Breast Imaging.

机构信息

Department of Radiology, Mayo Clinic, Rochester, MN.

出版信息

Semin Roentgenol. 2022 Apr;57(2):134-138. doi: 10.1053/j.ro.2021.12.006. Epub 2021 Dec 31.

DOI:10.1053/j.ro.2021.12.006
PMID:35523526
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9077005/
Abstract

Molecular breast imaging (MBI) is a nuclear medicine study performed with dedicated gamma camera systems optimized to image the uptake of Tc-99m sestamibi in the breast. MBI provides a relatively low-cost and simple functional breast imaging method that can identify breast cancers obscured by dense fibroglandular tissue on mammography. Recent studies have also found that background levels of uptake in benign dense tissue may provide breast cancer risk information. This article discusses the latest updates in MBI technology, recent evidence supporting its clinical use, and work in progress that may aid in wider adoption of MBI.

摘要

分子乳腺成像(MBI)是一种核医学研究,使用专门的伽马相机系统进行,该系统经过优化,可对 Tc-99m sestamibi 在乳房中的摄取情况进行成像。MBI 提供了一种相对低成本且简单的功能性乳房成像方法,可以识别在乳房 X 线摄影中被致密纤维腺体组织遮挡的乳腺癌。最近的研究还发现,良性致密组织中的摄取背景水平可能提供乳腺癌风险信息。本文讨论了 MBI 技术的最新更新、支持其临床应用的最新证据以及正在进行的工作,这些工作可能有助于更广泛地采用 MBI。

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本文引用的文献

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Let's Get Real about Molecular Breast Imaging and Radiation Risk.让我们正视分子乳腺成像与辐射风险。
Radiol Imaging Cancer. 2019 Sep 27;1(1):e190070. doi: 10.1148/rycan.2019190070. eCollection 2019 Sep.
2
Molecular Breast Imaging-guided Percutaneous Biopsy of Breast Lesions: A New Frontier on Breast Intervention.分子乳腺成像引导下乳腺病变的经皮活检:乳腺介入治疗的新前沿。
J Breast Imaging. 2020 Sep-Oct;2(5):484-491. doi: 10.1093/jbi/wbaa057. Epub 2020 Aug 11.
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Background Parenchymal Uptake on Molecular Breast Imaging and Breast Cancer Risk: A Cohort Study.
Radiol Imaging Cancer. 2024 Mar;6(2):e240006. doi: 10.1148/rycan.240006.
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Breast Cancer Detection Using a Low-Dose Positron Emission Digital Mammography System.使用低剂量正电子发射数字乳腺摄影系统进行乳腺癌检测。
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背景:分子乳腺成像的实质摄取与乳腺癌风险:队列研究。
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Diagnostic Performance of MRI, Molecular Breast Imaging, and Contrast-enhanced Mammography in Women with Newly Diagnosed Breast Cancer.MRI、分子乳腺成像和对比增强乳腺摄影在新诊断乳腺癌女性中的诊断性能。
Radiology. 2019 Dec;293(3):531-540. doi: 10.1148/radiol.2019190887. Epub 2019 Oct 29.
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Dose Reduction in Molecular Breast Imaging With a New Image-Processing Algorithm.应用新型图像处理算法降低分子乳腺成像剂量
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Comparison of Tc-Sestamibi Molecular Breast Imaging and Breast MRI in Patients With Invasive Breast Cancer Receiving Neoadjuvant Chemotherapy.Tc-Sestamibi 分子乳腺成像与接受新辅助化疗的浸润性乳腺癌患者的乳腺 MRI 对比。
AJR Am J Roentgenol. 2019 Oct;213(4):932-943. doi: 10.2214/AJR.18.20628. Epub 2019 Jun 5.
7
Guidelines for Quality Control Testing of Molecular Breast Imaging Systems.
J Nucl Med Technol. 2018 Dec;46(4):349-354. doi: 10.2967/jnmt.118.209221. Epub 2018 Jun 8.
8
BEST PRACTICES IN MOLECULAR BREAST IMAGING: A GUIDE FOR TECHNOLOGISTS.分子乳腺成像的最佳实践:技术人员指南。
J Nucl Med Technol. 2018 Feb 2. doi: 10.2967/jnmt.117.204263.
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First Clinical Experience Using Stereotactic Breast Biopsy Guided by Tc-Sestamibi.Tc-Sestamibi 引导下立体定向乳腺活检的首次临床应用经验
AJR Am J Roentgenol. 2017 Dec;209(6):1367-1373. doi: 10.2214/AJR.17.18083. Epub 2017 Apr 5.
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AJR Am J Roentgenol. 2017 Feb;208(2):275-283. doi: 10.2214/AJR.16.17131. Epub 2016 Oct 20.