Men Yutao, Liu Kaifeng, Liu Fulong, Zhang Chunqiu
Tianjin Key Laboratory for Advanced Mechatronic System Design and Intelligent Control, School of Mechanical Engineering, Tianjin University of Technology, Tianjin 300384, P. R. China.
National Demonstration Center for Experimental Mechanical and Electrical Engineering Education (Tianjin University of Technology), Tianjin 300384, P. R. China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2022 Apr 25;39(2):347-352. doi: 10.7507/1001-5515.202109073.
Cartilage surface fibrosis is an early sign of osteoarthritis and cartilage surface damage is closely related to load. The purpose of this study was to study the relationship between cartilage surface roughness and load. By applying impact, compression and fatigue loads on fresh porcine articular cartilage, the rough value of cartilage surface was measured at an interval of 10 min each time and the change rule of roughness before and after loading was obtained. It was found that the load increased the roughness of cartilage surface and the increased value was related to the load size. The time of roughness returning to the initial condition was related to the load type and the load size. The impact load had the greatest influence on the roughness of cartilage surface, followed by the severe fatigue load, compression load and mild fatigue load. This article provides reference data for revealing the pathogenesis of early osteoarthritis and preventing and treating articular cartilage diseases.
软骨表面纤维化是骨关节炎的早期迹象，且软骨表面损伤与负荷密切相关。本研究的目的是探讨软骨表面粗糙度与负荷之间的关系。通过对新鲜猪关节软骨施加冲击、压缩和疲劳负荷，每次间隔10分钟测量软骨表面的粗糙度值，得出加载前后粗糙度的变化规律。结果发现，负荷增加了软骨表面的粗糙度，增加值与负荷大小有关。粗糙度恢复到初始状态的时间与负荷类型和负荷大小有关。冲击负荷对软骨表面粗糙度的影响最大，其次是重度疲劳负荷、压缩负荷和轻度疲劳负荷。本文为揭示早期骨关节炎的发病机制及防治关节软骨疾病提供了参考数据。
