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本文引用的文献

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Aspirin and cancer survival: a systematic review and meta-analyses of 118 observational studies of aspirin and 18 cancers.阿司匹林与癌症生存率:对118项关于阿司匹林和18种癌症的观察性研究的系统评价和荟萃分析
Ecancermedicalscience. 2021 Jul 2;15:1258. doi: 10.3332/ecancer.2021.1258. eCollection 2021.
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Diagnostic criteria for cancer cachexia: reduced food intake and inflammation predict weight loss and survival in an international, multi-cohort analysis.癌症恶病质的诊断标准:国际多队列分析表明,减少食物摄入和炎症可预测体重减轻和生存。
J Cachexia Sarcopenia Muscle. 2021 Oct;12(5):1189-1202. doi: 10.1002/jcsm.12756. Epub 2021 Aug 27.
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Cancer cachexia in adult patients: ESMO Clinical Practice Guidelines.成人癌症恶病质:ESMO 临床实践指南。
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Interleukin-6 receptor blockade in patients with COVID-19: placing clinical trials into context.新型冠状病毒肺炎患者的白细胞介素-6受体阻断:临床试验背景分析
Lancet Respir Med. 2021 Jun;9(6):655-664. doi: 10.1016/S2213-2600(21)00139-9. Epub 2021 Apr 27.
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Comparison of the prognostic value of MUST, ECOG-PS, mGPS and CT derived body composition analysis in patients with advanced lung cancer.比较 MUST、ECOG-PS、mGPS 和 CT 衍生的身体成分分析在晚期肺癌患者中的预后价值。
Clin Nutr ESPEN. 2020 Dec;40:349-356. doi: 10.1016/j.clnesp.2020.08.003. Epub 2020 Sep 6.
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The relationship between the BMI-adjusted weight loss grading system and quality of life in patients with incurable cancer.不可治愈癌症患者的 BMI 调整体重减轻分级系统与生活质量之间的关系。
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An exploratory study examining the relationship between performance status and systemic inflammation frameworks and cytokine profiles in patients with advanced cancer.一项探索性研究,考察晚期癌症患者的体能状态与全身炎症框架及细胞因子谱之间的关系。
Medicine (Baltimore). 2019 Sep;98(37):e17019. doi: 10.1097/MD.0000000000017019.

癌症恶病质:一种营养相关还是系统性炎症综合征?

Cancer cachexia: a nutritional or a systemic inflammatory syndrome?

机构信息

Academic Unit of Surgery, School of Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK.

Institute of Cancer, University of Edinburgh, Edinburgh, UK.

出版信息

Br J Cancer. 2022 Aug;127(3):379-382. doi: 10.1038/s41416-022-01826-2. Epub 2022 May 6.

DOI:10.1038/s41416-022-01826-2
PMID:35523879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9073809/
Abstract

Cancer cachexia has long been perceived as a nutritional syndrome. However, nutritional interventions have continued to be ineffective. With the recent recognition of the importance of systemic inflammation in the definition of this syndrome and treatment, has the time come to consider whether this syndrome is primarily a manifestation of systemic inflammation with the consequent implications for future treatment?

摘要

癌症恶病质长期以来一直被认为是一种营养综合征。然而,营养干预一直没有效果。随着最近认识到全身炎症在该综合征的定义和治疗中的重要性,是否到了考虑这种综合征是否主要是全身炎症表现的时候了,以及这对未来治疗的影响?