Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Atatürk University, Erzurum, Turkey.
Private Zoom Dental Clinic, 06530, Ankara, Turkey.
Ir J Med Sci. 2022 Oct;191(5):2305-2310. doi: 10.1007/s11845-022-03020-y. Epub 2022 May 7.
Pure titanium and Ti6Al4V alloy have been in use as dental implant contemporarily. Trace element release from implant bodies is a possible health problem. Well-healed and osseointegrated intrabony implants are only in contact with bone and blood, but in the case of periimplantitis, the possibility of corrosion and the release of trace elements from dental implant surfaces increases due to contact with external factors.
The aim of this study is to evaluate the trace element levels in the blood serum and saliva of patients who have dental implants with periimplantitis compared with the control group.
This study included 25 patients diagnosed with periimplantitis and 25 participants with healthy osseointegrated implants as the control group. The trace element levels in blood serum and saliva were measured by inductively coupled plasma-mass spectrometry (ICP-MS) and results were analyzed statistically.
There is no statistically significant difference between groups for saliva samples except the aluminum (Al) levels of the study group are significantly lower than the control group (p < 0.05) and the mercury (Hg) levels of the study group are significantly higher than the control group (p < 0.05). On the other hand, there is a significant decrease in titanium (Ti), chromium (Cr), and iodine (I) in the blood serum samples of the study group (p < 0.05). There is no significant difference between the groups for other measured trace elements in the blood serum (p > 0.05).
There is no statistically significant increase in titanium or aluminum levels in the study group compared with the control group.
纯钛和 Ti6Al4V 合金目前被用作牙科植入物。植入体中微量元素的释放可能是一个健康问题。愈合良好且骨整合的骨内植入物仅与骨和血液接触，但在种植体周围炎的情况下，由于与外部因素接触，种植体表面腐蚀和微量元素释放的可能性增加。
本研究旨在评估患有种植体周围炎的患者与对照组相比，其血清和唾液中的微量元素水平。
本研究包括 25 名被诊断为种植体周围炎的患者和 25 名具有健康骨整合植入物的参与者作为对照组。通过电感耦合等离子体质谱法（ICP-MS）测量血清和唾液中的微量元素水平，并进行统计学分析。
除研究组的唾液样本中的铝（Al）水平明显低于对照组（p<0.05），研究组的汞（Hg）水平明显高于对照组（p<0.05）外，两组间的唾液样本无统计学差异。另一方面，研究组的血清样本中的钛（Ti）、铬（Cr）和碘（I）显著减少（p<0.05）。血清中其他测量的微量元素在两组之间无显著差异（p>0.05）。
与对照组相比，研究组的钛或铝水平没有统计学上的显著增加。
