Department of Ophthalmology, Copenhagen University Hospital - Rigshospitalet-Glostrup, Glostrup, Denmark.
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Clin Exp Ophthalmol. 2022 Aug;50(6):590-597. doi: 10.1111/ceo.14092. Epub 2022 May 16.
To report long-term biometric and refractive outcomes in a group of Danish children after surgery for childhood cataract.
Children between 7 and 18 years who had undergone uni- or bilateral cataract surgery at the Department of Ophthalmology, Rigshospitalet, Denmark, were examined in this cross-sectional study. Swept source optical coherence tomography (OCT) based optical biometry (IOLmaster 700) and anterior tomography (Pentacam) was performed. Healthy fellow eyes from those with unilateral cataract were used as controls.
We included 56 children in the study with a median age at surgery of 43.8 months (1.6-137.6). The amount of higher order aberrations was significantly increased in operated eyes (median root mean square 0.461 μm [range 0.264-1.484]) compared with non-operated eyes (median root mean square 0.337 μm [range 0.162-0.498], p < 0.001). Younger age at surgery was positively associated with more higher order aberrations at follow-up (p < 0.001), but we found no significant associations between the amount of higher order aberrations and visual acuity or contrast vision. Longer axial length was associated to glaucoma while shorter axial length was associated to strabismus (p < 0.001).
Eyes operated for childhood cataract have higher order aberrations compared with non-operated eyes. Higher order aberrations are complex refractive errors that cannot be corrected by normal lenses and may contribute to poor visual outcomes for the children. We found an association between young age at surgery and higher order aberrations.
报告丹麦一组儿童白内障手术后长期生物测量和屈光结果。
本横断面研究检查了丹麦里格医院眼科接受单侧或双侧白内障手术的 7 至 18 岁儿童。使用基于扫频源光相干断层扫描（OCT）的光学生物测量仪（IOLmaster 700）和前断层扫描仪（Pentacam）进行检查。将单侧白内障儿童的健康对侧眼用作对照。
我们纳入了 56 名研究儿童，手术时的中位年龄为 43.8 个月（1.6-137.6）。与未手术眼相比，手术眼的高阶像差明显增加（中位数均方根 0.461μm[范围 0.264-1.484]）（中位数均方根 0.337μm[范围 0.162-0.498]，p<0.001）。手术时年龄越小，随访时高阶像差越大（p<0.001），但我们未发现高阶像差与视力或对比敏感度之间存在显著相关性。较长的眼轴与青光眼有关，而较短的眼轴与斜视有关（p<0.001）。
与未手术眼相比，儿童白内障术后眼存在高阶像差。高阶像差是无法通过普通镜片矫正的复杂折射误差，可能导致儿童视觉结果不佳。我们发现手术年龄与高阶像差之间存在关联。
