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单极电凝治疗出血性胃溃疡的疗效:一项对照试验。

Efficacy of monopolar electrocoagulation in the treatment of bleeding gastric ulcer: a controlled trial.

作者信息

Moretó M, Zaballa M, Ibáñez S, Setién F, Figa M

出版信息

Endoscopy. 1987 Mar;19(2):54-6. doi: 10.1055/s-2007-1018234.

DOI:10.1055/s-2007-1018234
PMID:3552639
Abstract

With the aim of evaluating, in a controlled prospective fashion, the efficacy of monopolar electrocoagulation in the emergency treatment of bleeding gastric and stomal ulcers, 37 patients were studied: 16 were electrocoagulated (EC group) while the remaining 21 were treated by conventional methods (control group). The hemorrhage recurred in only one of the 16 patients belonging to the EC group, but in 11 of the 21 control patients (p less than 0.0005). Transfusion requirements were also reduced in the EC group (p less than 0.05), with no significant difference in relation to mortality. Stratifying the results according to hemorrhagic activity, electrocoagulation should be clearly effective in those patients with spurting hemorrhage, taking into account several limitations: deep ulcers bearing gross vessels, and lack of cooperation by the patient. Prophylactic treatment of the bleeding ulcer with a visible non-spurting vessel may be indicated whenever we make a proper selection of the patients with a greater possibility of hemorrhagic recurrence.

摘要

为了以对照前瞻性方式评估单极电凝在胃和吻合口溃疡出血急诊治疗中的疗效,对37例患者进行了研究:16例接受电凝治疗(电凝组),其余21例采用传统方法治疗(对照组)。电凝组的16例患者中只有1例再次出血,而对照组的21例患者中有11例再次出血(p<0.0005)。电凝组的输血需求也有所减少(p<0.05),死亡率无显著差异。根据出血活动程度对结果进行分层,考虑到一些局限性:有粗大血管的深部溃疡以及患者不配合,电凝对喷射性出血的患者显然有效。只要我们正确选择出血复发可能性较大的患者,对于有可见非喷射性血管的出血性溃疡可进行预防性治疗。

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Gut. 1998 Apr;42(4):462-9. doi: 10.1136/gut.42.4.462.
2
Current management of bleeding peptic ulcer. A review.
Drugs. 1993 Aug;46(2):269-80. doi: 10.2165/00003495-199346020-00005.
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Endoscopic intervention in bleeding peptic ulcer.内镜下治疗出血性消化性溃疡。
Gut. 1995 Aug;37(2):161-4. doi: 10.1136/gut.37.2.161.
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Emergency endoscopy: a basis for therapeutic decisions in the treatment of severe gastroduodenal bleeding.急诊内镜检查:重症胃十二指肠出血治疗中治疗决策的基础。
World J Surg. 1989 Sep-Oct;13(5):592-7. doi: 10.1007/BF01658876.
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Bleeding peptic ulcers.出血性消化性溃疡
BMJ. 1991 Jun 15;302(6790):1417-8. doi: 10.1136/bmj.302.6790.1417.
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Bleeding peptic ulcer--endoscopic and pharmacological management.出血性消化性溃疡——内镜及药物治疗
Postgrad Med J. 1991 Jul;67(789):606-12. doi: 10.1136/pgmj.67.789.606.
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Endoscopic management of nonvariceal gastrointestinal bleeding.非静脉曲张性上消化道出血的内镜治疗
World J Surg. 1992 Nov-Dec;16(6):1025-33. doi: 10.1007/BF02067057.