Protell R L, Gilbert D A, Silverstein F E, Jensen D M, Hulett F M, Auth D C
Gastroenterology. 1981 Mar;80(3):451-5.
A prospective, randomized, controlled experiment using a canine model of severely bleeding gastric ulcer was performed to compare the hemostatic efficacy and tissue damage produced by one bipolar and two monopolar electrodes. Both monopolar electrodes were insulated to their tips; they differed with respect to their surface area (3 mm2 vs. 4 mm2). The force of electrode application was controlled. An analog computer monitored the energy per electrode application and predetermined the duration of each application. Fifty-nine standard acute bleeding ulcers were made and treated one at a time in six heparinized foxhounds at sterile laparotomy. Treatment was randomized to the bipolar or to one of the monopolar electrodes within each of three bleeding strata. No significant difference was observed in hemostatic efficacy among the three electrodes. Treated ulcers were examined histologically after 5 to 7 days to determine the maximum tissue damage produced: Bipolar electrocoagulation caused significantly less damage than electrocoagulation with either monopolar electrode. We conclude that with these electrodes, bipolar electrocoagulation is equally effective for stopping bleeding but results in less tissue injury than monopolar electrocoagulation in this experimental model.
采用严重出血性胃溃疡犬模型进行了一项前瞻性、随机、对照实验，以比较一种双极电极和两种单极电极的止血效果及产生的组织损伤。两种单极电极的尖端均绝缘；它们的表面积不同（3平方毫米对4平方毫米）。电极施加的力得到控制。一台模拟计算机监测每次电极施加的能量，并预先确定每次施加的持续时间。在无菌剖腹手术中，对六只肝素化的猎狐犬制作了59个标准急性出血性溃疡，并每次治疗一个。在三个出血层中，治疗随机分配至双极电极或其中一种单极电极。三种电极在止血效果上未观察到显著差异。在5至7天后对治疗的溃疡进行组织学检查，以确定产生的最大组织损伤：双极电凝造成的损伤明显小于任何一种单极电极电凝。我们得出结论，在该实验模型中，使用这些电极时，双极电凝在止血方面同样有效，但比单极电凝导致的组织损伤更小。
