Department of Pediatrics, Peking University First Hospital, Beijing, China.
Department of Pediatrics, Peking University First Hospital, Beijing, China; Department of Pediatric Respiratory Medicine, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Chest. 2022 May;161(5):e273-e278. doi: 10.1016/j.chest.2021.12.639.
An 11-month-old boy was admitted to our hospital because of "recurrent cough with intermittent dyspnea for more than 8 months, aggravated for 1 month." The baby began experiencing a recurrent milk-choking problem within 1.5 months after birth. He had been hospitalized four times, but the symptoms recurred. One month previously, the symptoms were aggravated and a chest CT scan performed at outside hospital showed interstitial changes. Pediatric bronchoscopy revealed bronchial inflammatory features, with hemosiderin-laden macrophages being found in BAL fluid (BALF). Also, periodic acid-Schiff (PAS) staining showed positive results, which indicated the possibility of pulmonary alveolar proteinosis (PAP) or idiopathic pulmonary hemosiderosis (IPH).
一名 11 个月大的男婴因“反复咳嗽伴间歇性呼吸困难 8 个月余，加重 1 个月”入院。患儿生后 1.5 月即开始反复出现呛奶问题，曾住院 4 次，但症状反复发作。1 个月前症状加重，外院胸部 CT 显示间质性改变。儿科支气管镜检查显示支气管炎症特征，支气管肺泡灌洗液（BALF）中可见含铁血黄素的巨噬细胞。过碘酸雪夫（PAS）染色阳性，提示肺肺泡蛋白沉积症（PAP）或特发性肺含铁血黄素沉着症（IPH）可能。
