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鞘内泵。

Intrathecal Pumps.

机构信息

Department of Anesthesiology, University of Virginia, Charlottesville, VA, USA.

Pain Medicine Fellowship, Pain Management Center, Fontaine Research Park, Third Floor, 545 Ray C Hunt Drive, Charlottesville, VA 22908, USA.

出版信息

Phys Med Rehabil Clin N Am. 2022 May;33(2):409-424. doi: 10.1016/j.pmr.2022.01.004.

Abstract

Intrathecal drug delivery systems are a well-established intervention for chronic pain. The localized delivery of analgesics allows for reduced side effect profiles and pain scores in patients with chronic pain. Given their proven benefits and the development of novel intrathecal medications, intrathecal drug delivery systems are being used earlier in chronic pain management treatment pathways. Success is reliant on proper patient selection and mitigating the risks of various adverse events stemming from the implantation procedure, medications, and the device itself. This article discusses patient selection criteria, medication selection, risks, complications, supporting data, and future directions of intrathecal drug delivery systems.

摘要

鞘内药物递送系统是一种成熟的慢性疼痛干预手段。通过将镇痛药局部递送给患者,可以减轻慢性疼痛患者的副作用和疼痛评分。鉴于鞘内药物递送系统的益处已得到证实,以及新型鞘内药物的发展,该系统在慢性疼痛管理治疗途径中的应用越来越早。成功依赖于正确的患者选择,以及减轻与植入手术、药物和设备本身相关的各种不良事件的风险。本文讨论了鞘内药物递送系统的患者选择标准、药物选择、风险、并发症、支持数据和未来方向。

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