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急性脑梗死患者认知障碍及神经功能恢复的急救护理与监测流程。

An emergency nursing and monitoring procedure on cognitive impairment and neurological function recovery in patients with acute cerebral infarction.

机构信息

Department of Emergency, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, Jiangsu, China.

出版信息

NeuroRehabilitation. 2022;51(1):161-170. doi: 10.3233/NRE-210310.

Abstract

BACKGROUND

The optimization and standardization of emergency nursing and monitoring procedures are of great significance for thrombolytic treatment of acute cerebral infarction.

OBJECTIVE

Studies on the emergency nursing and monitoring procedure on cognitive impairment and neurological function in patients with acute cerebral infarction are still limited.

METHODS

The study was a randomized controlled trial and 134 patients with acute cerebral infarction were recruited. They were randomly arranged into the control group (n = 67) receiving normal nursing procedure and the intervention group (n = 67) receiving emergency nursing and monitoring procedure after pre-intervention assessment. The cognitive impairment, neurological function and levels of inflammatory biomarkers and neuron-specific enolase of the participants were evaluated and analyzed.

RESULTS

Emergency nursing and monitoring procedure improved Mini-mental State Examination and Montreal Cognitive Assessment scores of patients with cerebral infraction compared with the control group. It also improved the scores of National Institutes of Health Stroke Scale, activities of daily living scale, Fugl-Meyer scale in the participants. Emergency nursing and monitoring procedure led to significantly decreased neuron-specific enolase and inflammatory cytokines in the serum of the participants.

CONCLUSION

Emergency nursing and monitoring procedure are beneficial for cognitive impairment and neurological function recovery in patients with acute cerebral infarction.

摘要

背景

优化和规范急诊护理及监测流程对于急性脑梗死的溶栓治疗具有重要意义。

目的

关于急性脑梗死患者认知障碍和神经功能的急诊护理及监测流程研究仍较为有限。

方法

本研究为随机对照试验,共纳入 134 例急性脑梗死患者,在进行预干预评估后,将其随机分为对照组(n=67)接受常规护理流程和观察组(n=67)接受急诊护理及监测流程。评估并分析患者的认知障碍、神经功能以及炎症生物标志物和神经元特异性烯醇化酶水平。

结果

与对照组相比,急诊护理及监测流程可改善脑梗死患者的简易精神状态检查和蒙特利尔认知评估评分,还可改善患者的国立卫生研究院卒中量表、日常生活活动量表、Fugl-Meyer 量表评分。急诊护理及监测流程可使患者血清中的神经元特异性烯醇化酶和炎症细胞因子显著降低。

结论

急诊护理及监测流程有利于急性脑梗死患者认知障碍和神经功能的恢复。

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