Occupational Sleep Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Center for Research on Occupational Disease, Tehran University of Medical Sciences, Tehran, Iran.
Work. 2022;72(2):595-600. doi: 10.3233/WOR-210056.
Shift work may be associated with insulin resistance.
This study aimed to investigate the potential association between shift work and the homeostatic model assessment of insulin resistance (HOMA-IR) index in professional drivers.
A total of four hundred fifty-three professional drivers were invited to participate in the study within a periodic medical examination in the occupational setting. One hundred seventy-seven daytime workers were compared with 175 night shifts and 101 early morning shift drivers. Demographic, occupational, and medical examination including blood pressure, anthropometric data was assessed. Measurement of serum insulin, fasting blood glucose and lipid profile were done for all drivers.
Compared with day workers, night shift and early morning shift drivers displayed higher levels of HOMA-IR. Metabolic syndrome was found to be significantly increased in night workers. In linear regression analysis, insulin resistance was correlated with shift work independently of demographic and occupational characteristics.
The study revealed that shift work could be a risk factor in developing the risk of metabolic syndrome and insulin resistance. Suggestively, health strategies such as structured lifestyle counseling in occupational health settings are warranted to improve and modify cardiometabolic risk factors.
轮班工作可能与胰岛素抵抗有关。
本研究旨在调查轮班工作与职业驾驶员稳态模型评估的胰岛素抵抗（HOMA-IR）指数之间的潜在关联。
在职业环境中的定期体检中，共邀请了 453 名职业驾驶员参与研究。将 177 名白班工人与 175 名夜班和 101 名早班司机进行比较。评估了人口统计学、职业和医学检查，包括血压、人体测量数据。对所有驾驶员进行血清胰岛素、空腹血糖和血脂谱的测量。
与白班工人相比，夜班和早班司机的 HOMA-IR 水平更高。代谢综合征在夜班工人中明显增加。在线性回归分析中，胰岛素抵抗与轮班工作独立于人口统计学和职业特征相关。
本研究表明，轮班工作可能是代谢综合征和胰岛素抵抗风险增加的一个危险因素。建议在职业健康环境中实施结构化的生活方式咨询等健康策略，以改善和调整心血管代谢风险因素。
