Removable Prosthesis and Dental Materials Area, Faculty of Dentistry, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brazil.
Department of Dental Materials and Prosthodontics, Dental School, Araçatuba, Brazil.
Photobiomodul Photomed Laser Surg. 2022 Jul;40(7):440-453. doi: 10.1089/photob.2021.0092. Epub 2022 May 6.
Despite the association, possible causality, and contradictory results, numerous studies evaluate photobiomodulation (PBM) therapy on the process of human bone healing. It is of paramount importance to review the available literature to elucidate the effect of laser on the bone healing process in dentistry. This systematic review analyzes the effectiveness of PBM therapy to improve bone healing in dentistry. A systematic search of studies published up to September 2021 and listed in PubMed, Cochrane Library, and Embase databases and registered on PROSPERO (CRD42020212790). Twenty-five studies were selected. The most used device was diode laser. PBM therapy parameters varied greatly. From the 25 selected studies, 17 had the primary outcome bone healing. Of these, 11 studies revealed improvement in bone healing with PBM therapy and six studies suggested no effect. The other eight studies evaluated secondary parameters. In seven studies, some of the clinical parameters were improved with the PBM therapy. Within the limitations of this systematic review, bone healing in dentistry was improved with the use of PBM. PBM therapy can promote anti-inflammatory and analgesic effects, improve healing, as well as enhance quality of life related to oral health. Within the areas analyzed in dentistry, laser parameters varied greatly, becoming difficult to consider a definite protocol as a proper one.
尽管存在关联、可能的因果关系和相互矛盾的结果，但许多研究都评估了光生物调节（PBM）疗法在人类骨骼愈合过程中的作用。至关重要的是，要回顾现有的文献，以阐明激光对牙科中骨骼愈合过程的影响。本系统评价分析了 PBM 疗法在改善牙科骨愈合方面的有效性。对截至 2021 年 9 月在 PubMed、Cochrane Library 和 Embase 数据库中发表的研究进行了系统搜索，并在 PROSPERO（CRD42020212790）上进行了注册。共选择了 25 项研究。最常用的设备是二极管激光。PBM 治疗参数差异很大。在所选择的 25 项研究中，有 17 项的主要结果为骨愈合。其中，11 项研究表明 PBM 疗法可改善骨愈合，6 项研究表明无效果。其他 8 项研究评估了次要参数。在 7 项研究中，PBM 治疗改善了一些临床参数。在本系统评价的限制范围内，牙科中的骨愈合得到了改善。PBM 疗法可以促进抗炎和镇痛作用，改善愈合，并提高与口腔健康相关的生活质量。在牙科分析的领域中，激光参数差异很大，很难考虑一个确定的方案作为合适的方案。
