- BuOK催化芴与醇的烷基化反应：一条合成9-单烷基芴衍生物的高度绿色的路线。

-BuOK-catalysed alkylation of fluorene with alcohols: a highly green route to 9-monoalkylfluorene derivatives.

作者信息

Fan Jiang-Tao, Fan Xin-Heng, Gao Cai-Yan, Wang Zhenpeng, Yang Lian-Ming

机构信息

Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences Beijing 100190 China

University of Chinese Academy of Sciences Beijing 100049 China.

出版信息

RSC Adv. 2019 Nov 4;9(61):35913-35916. doi: 10.1039/c9ra07557g. eCollection 2019 Oct 31.

DOI:10.1039/c9ra07557g

PMID:35528057

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9074706/

Abstract

A simple, mild and efficient protocol was developed for the alkylation of fluorene with alcohols in the presence of -BuOK as catalyst, affording the desired 9-monoalkylfluorenes with near quantitative yields in most cases.

摘要

开发了一种简单、温和且高效的方法，用于在叔丁醇钾作为催化剂存在的情况下，芴与醇进行烷基化反应，在大多数情况下能以接近定量的产率得到所需的9-单烷基芴。