Yu Aili, Zhao Qiuhong, Qu Yimeng, Liu Guohua
Department of ICU, Inner Mongolia Xing'anmeng People's Hospital, Ulanhot, 137400 Inner Mongolia, China.
Appl Bionics Biomech. 2022 Apr 26;2022:3472405. doi: 10.1155/2022/3472405. eCollection 2022.
This study was aimed to explore the renal Doppler ultrasound in the evaluation of renal function in patients with sepsis. Fifty patients with sepsis or septic shock were classified into the acute kidney injury (AKI) group (n =25) and the non-AKI group (n =25) according to whether they had AKI. The measurements of renal resistance index (RRI) and power Doppler ultrasound (PDU) were performed on all patients within 7 days of admission to the intensive care unit (ICU). The patient's renal function was assessed. The results showed that the RRI of the two groups showed a slight upward trend over time, and the RRI of the AKI group was higher than that of the non-AKI group. After 7 days in AKI group, the areas under the receiver operating characteristic (ROC) curves of RRI were 0.745, 0.683, 0.729, 0.856, 0.793, 0.819, and 0.836 (P <0.05). There were no statistically considerable differences in areas under ROC curves between the two groups (P >0.05). The grouping of AKI and the time were both fixed effects, and the individual patients were randomized effects. Besides, the linear models were statistically analyzed. The results showed that the differences between the two groups were statistically insignificant (P >0.05). There was no significant difference in the PDU scores measured at different times within 7 days after ICU admission between the two groups (P >0.05). In conclusion, renal Doppler ultrasound had a good adoption effect in the evaluation of the renal function of patients with severe sepsis, which is worth promoting in clinical practice.
本研究旨在探讨肾脏多普勒超声在评估脓毒症患者肾功能中的应用。50例脓毒症或脓毒性休克患者根据是否发生急性肾损伤（AKI）分为急性肾损伤组（n = 25）和非急性肾损伤组（n = 25）。在重症监护病房（ICU）入院7天内对所有患者进行肾阻力指数（RRI）和能量多普勒超声（PDU）测量，并评估患者的肾功能。结果显示，两组的RRI均随时间呈轻微上升趋势，且急性肾损伤组的RRI高于非急性肾损伤组。急性肾损伤组在7天后，RRI的受试者工作特征（ROC）曲线下面积分别为0.745、0.683、0.729、0.856、0.793、0.819和0.836（P <0.05）。两组之间ROC曲线下面积无统计学显著差异（P>0.05）。急性肾损伤分组和时间均为固定效应，个体患者为随机效应。此外，对线性模型进行了统计分析。结果显示，两组之间的差异无统计学意义（P>0.05）。两组在ICU入院后7天内不同时间测量的PDU评分无显著差异（P>0.05）。综上所述，肾脏多普勒超声在评估严重脓毒症患者肾功能方面具有良好的应用效果，值得在临床实践中推广。
