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黏液纤维肉瘤或黏液瘤:恶性转化还是误诊。

Myxofibrosarcoma or myxoma: malignant transformation or misdiagnosis.

作者信息

Das Aryakamal, Saha Atanu, Pattari Sanjib, Narayan Pradeep

机构信息

Department of Cardiac Surgery, Rabindranath Tagore International Institute of Cardiac Sciences, Narayana Health, Kolkata, India.

Department of Pathology, Rabindranath Tagore International Institute of Cardiac Sciences, Narayana Health, Kolkata, India.

出版信息

Indian J Thorac Cardiovasc Surg. 2022 May;38(3):290-293. doi: 10.1007/s12055-021-01298-8. Epub 2022 Jan 11.

DOI:10.1007/s12055-021-01298-8
PMID:35529008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9023637/
Abstract

Inadequate excision, seeding, multicentricity and malignancy are often ascribed for recurrence of atrial myxomas. Differentiation between benign myxomas and malignant myxofibrosarcomas can be challenging, and a high index of clinical suspicion and vimentin staining on immunohistochemistry is needed to confirm the diagnosis. Early recurrence is common in these patients and completeness of excision is the key. Prognosis despite successful excision is poor. We report a benign atrial myxoma in a young female patient which upon recurrence turned out to be a myxofibrosarcoma.

摘要

切除不彻底、种植转移、多中心性和恶性变常被认为是心房黏液瘤复发的原因。区分良性黏液瘤和恶性黏液纤维肉瘤具有挑战性,需要高度的临床怀疑指数和免疫组化中的波形蛋白染色来确诊。这些患者早期复发很常见,完整切除是关键。尽管成功切除,预后仍较差。我们报告了一名年轻女性患者的良性心房黏液瘤,其复发后结果为黏液纤维肉瘤。

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Successful multidisciplinary clinical approach and molecular characterization by whole transcriptome sequencing of a cardiac myxofibrosarcoma: A case report.心脏黏液纤维肉瘤的成功多学科临床方法及全转录组测序的分子特征分析:一例报告
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Primary cardiac myxofibrosarcoma: case report, literature review and pooled analysis.原发性心脏黏液纤维肉瘤:病例报告、文献复习及汇总分析。
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