Handryastuti Setyo, Silvana Sisca, Yunus Reyhan Eddy, Taufiqqurrachman Iqbal, Rafli Achmad
Department of Child Health, Dr.Cipto Mangunkusumo Tertiary General Hospital, Faculty of Medicine Universitas Indonesia Jakarta, Indonesia.
HKBP Nommensen University, Medan, Indonesia.
Child Neurol Open. 2022 May 3;9:2329048X221095699. doi: 10.1177/2329048X221095699. eCollection 2022 Jan-Dec.
Acute necrotizing encephalopathy of childhood (ANEC) is a rare condition of encephalopathy which commonly occurs in healthy children. This case report will discuss the diagnostic approach in a female child, three years old, with neurologic deficits. The diagnostic approach of ANEC consists of clinical manifestation, laboratory examination, cerebrospinal fluid (CSF) analysis, and neuroimaging interpretation. The patient had high liver enzyme, normal CSF analysis with appearances of edema, hemorrhage and necrosis in serial brain magnetic resonance imaging (MRI).
儿童急性坏死性脑病（ANEC）是一种罕见的脑病，常见于健康儿童。本病例报告将讨论一名3岁有神经功能缺损女童的诊断方法。ANEC的诊断方法包括临床表现、实验室检查、脑脊液（CSF）分析和神经影像学解读。该患者肝酶升高，脑脊液分析正常，连续脑部磁共振成像（MRI）显示有水肿、出血和坏死表现。
