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复发性原发性膀胱恶性黑色素瘤;病例报告

Recurrent primary malignant melanoma of the urinary bladder; a case report.

作者信息

Behtash Negar, Guitinavard Fateme, Ahmadi Navid, Bizhanzadeh Soroor

机构信息

Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Urol Case Rep. 2022 Feb 5;42:102026. doi: 10.1016/j.eucr.2022.102026. eCollection 2022 May.

DOI:10.1016/j.eucr.2022.102026
PMID:35530537
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9073205/
Abstract

Primary malignant melanoma (PMM) of the urinary bladder is a rare disease. Symptoms include gross hematuria and irritative LUTS. The diagnosis is made with cystoscopy and TURBT. Treatment options include TURBT and adjuvant therapies. We present a 61-year-old female who was referred with persistent irritative LUTS without gross or microscopic hematuria. After undergoing cystoscopy, TURBT, and extensive workup, she was diagnosed with PMM of the urinary bladder. Due to her past medical history, recurrent PMM of the urinary bladder was the final diagnosis. She refused to receive further treatment or refer for follow-up.

摘要

膀胱原发性恶性黑色素瘤(PMM)是一种罕见疾病。症状包括肉眼血尿和刺激性下尿路症状(LUTS)。通过膀胱镜检查和经尿道膀胱肿瘤切除术(TURBT)进行诊断。治疗选择包括TURBT和辅助治疗。我们报告一名61岁女性,因持续存在刺激性LUTS就诊,无肉眼或镜下血尿。在接受膀胱镜检查、TURBT及全面检查后,她被诊断为膀胱PMM。鉴于她的既往病史,最终诊断为复发性膀胱PMM。她拒绝接受进一步治疗或转诊进行随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c054/9073205/5b0e519ddaaa/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c054/9073205/5b0e519ddaaa/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c054/9073205/5b0e519ddaaa/gr1.jpg

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本文引用的文献

1
Primary Malignant Melanoma of the Urinary Bladder.膀胱原发性恶性黑色素瘤
Cureus. 2021 Mar 23;13(3):e14067. doi: 10.7759/cureus.14067.
2
Immunotherapy in non-muscle-invasive bladder cancer: current status and future directions.非肌肉浸润性膀胱癌的免疫治疗:现状与未来方向。
World J Urol. 2021 May;39(5):1319-1329. doi: 10.1007/s00345-020-03474-8. Epub 2020 Oct 15.
3
Spotting the pigmented 'Monster': primary melanoma in urinary bladder.发现色素沉着的“怪物”:原发性膀胱黑色素瘤
BMJ Case Rep. 2019 Dec 23;12(12):e231950. doi: 10.1136/bcr-2019-231950.
4
Primary malignant melanoma of the urinary bladder: clinical, morphological, and molecular analysis of five cases.膀胱原发性恶性黑色素瘤:5例临床、形态学及分子分析
Melanoma Res. 2016 Dec;26(6):616-624. doi: 10.1097/CMR.0000000000000300.
5
Melanoma of the urinary bladder: a review of the literature.膀胱黑色素瘤:文献综述
Surg Res Pract. 2014;2014:605802. doi: 10.1155/2014/605802. Epub 2014 Jan 12.