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鼻背和鼻尖原发性皮肤间变性大细胞淋巴瘤

Primary Cutaneous Anaplastic Large Cell Lymphoma of the Nasal Dorsum and Nasal Tip.

作者信息

Michali Maria C, Tsikou Alkistis T, Tsafaras Charalampos E, Kastanioudaki Polyniki I, Komnos Ioannis D

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Ioannina, Ioannina, GRC.

Department of Otorhinolaryngology, Head and Neck Surgery, Universith Hospital of Ioannina, Ioannina, GRC.

出版信息

Cureus. 2022 Apr 4;14(4):e23811. doi: 10.7759/cureus.23811. eCollection 2022 Apr.

DOI:10.7759/cureus.23811
PMID:35530829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9067410/
Abstract

Primary cutaneous anaplastic large-cell lymphoma (C-ALCL) is described as a non-Hodgkin lymphoma that affects only the skin, with no evidence of an extracutaneous disease during the first six months following the diagnosis. We present an unusual case of a 53-year-old man with developed fever and a rapidly increasing ulcerated skin lesion located on the nasal dorsum and nasal tip. The nasal endoscopy revealed a reddish polypoid lesion over the anterior edge of the superior turbinate which had extended through the roof of the nasal cavity in the adjacent area of the nasal septum.

摘要

原发性皮肤间变性大细胞淋巴瘤(C-ALCL)被描述为一种仅累及皮肤的非霍奇金淋巴瘤,在诊断后的前六个月内无皮肤外疾病的证据。我们报告一例不寻常的病例,一名53岁男性,出现发热,鼻背和鼻尖有一处迅速增大的溃疡性皮肤病变。鼻内镜检查发现上鼻甲前缘有一个红色息肉样病变,该病变已延伸至鼻中隔相邻区域的鼻腔顶部。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a0b/9067410/4c11d6773cfb/cureus-0014-00000023811-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a0b/9067410/5ba06b49d2f6/cureus-0014-00000023811-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a0b/9067410/aa348311dbd4/cureus-0014-00000023811-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a0b/9067410/9a25d2d8f2be/cureus-0014-00000023811-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a0b/9067410/4c11d6773cfb/cureus-0014-00000023811-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a0b/9067410/5ba06b49d2f6/cureus-0014-00000023811-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a0b/9067410/aa348311dbd4/cureus-0014-00000023811-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a0b/9067410/9a25d2d8f2be/cureus-0014-00000023811-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a0b/9067410/4c11d6773cfb/cureus-0014-00000023811-i04.jpg

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本文引用的文献

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Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training.老年人原发性皮肤间变性大细胞淋巴瘤(pcALCL)与运动训练的重要性。
Int J Environ Res Public Health. 2020 Jan 29;17(3):839. doi: 10.3390/ijerph17030839.
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Primary cutaneous CD30-positive anaplastic large-cell lymphoma of the external auditory canal.外耳道原发性皮肤CD30阳性间变性大细胞淋巴瘤
Ear Nose Throat J. 2012 Dec;91(12):E10-2. doi: 10.1177/014556131209101214.
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Perils and pitfalls regarding differential diagnosis and treatment of primary cutaneous anaplastic large-cell lymphoma.
原发性皮肤间变性大细胞淋巴瘤鉴别诊断与治疗中的风险与陷阱
ScientificWorldJournal. 2011 May 5;11:1048-55. doi: 10.1100/tsw.2011.80.
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Primary cutaneous anaplastic large cell lymphoma of the nasal tip in a child.儿童鼻尖原发性皮肤间变性大细胞淋巴瘤
Pediatr Dermatol. 2011 Sep-Oct;28(5):570-5. doi: 10.1111/j.1525-1470.2010.01245.x. Epub 2010 Sep 1.
5
Bone marrow examination has limited value in the staging of patients with an anaplastic large cell lymphoma first presenting in the skin. Retrospective analysis of 107 patients.骨髓检查对首发于皮肤的间变性大细胞淋巴瘤患者的分期价值有限。对107例患者的回顾性分析。
Br J Dermatol. 2008 Nov;159(5):1148-51. doi: 10.1111/j.1365-2133.2008.08812.x. Epub 2008 Sep 6.
6
ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project.ALK-间变性大细胞淋巴瘤在临床和免疫表型上与ALK+间变性大细胞淋巴瘤及外周T细胞淋巴瘤(未另行指定)均不同:来自国际外周T细胞淋巴瘤项目的报告
Blood. 2008 Jun 15;111(12):5496-504. doi: 10.1182/blood-2008-01-134270. Epub 2008 Apr 2.
7
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Clin Exp Dermatol. 2007 Nov;32(6):668-71. doi: 10.1111/j.1365-2230.2007.02477.x.
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Am J Dermatopathol. 2005 Jun;27(3):217-23. doi: 10.1097/01.dad.0000154414.46851.18.
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Pediatr Dev Pathol. 2005 Jan-Feb;8(1):52-60. doi: 10.1007/s10024-004-8087-6. Epub 2005 Feb 23.
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