Alenazi Mohammed S, Alqahtani Ali M, Ahmad Mohammad M, Almalki Eyad M, AlMutair Angham, Almalki Mussa
Diabetes and Endocrine Treatment Center, Prince Sultan Military Medical City, Riyadh, SAU.
Obesity, Endocrine, and Metabolism Center, King Fahad Medical City, Riyadh, SAU.
Cureus. 2022 Apr 5;14(4):e23864. doi: 10.7759/cureus.23864. eCollection 2022 Apr.
Puberty is a developmental stage characterized by the appearance of secondary sexual characteristics which leads to complete physical, psychosocial, and sexual maturation. The current practice of hormonal therapy to induce puberty in adolescent males is based on published consensus and expert opinion. Evidence-based guidelines on optimal timing and regimen in puberty induction in males are lacking, and this reflects some discrepancies in practice among endocrinologists. It is worth mentioning that the availability of various hormonal products in markets, their different routes of administration, and patients/parents' preference also have an impact on clinical decisions. This review outlines the current clinical approach to delayed puberty in boys with an emphasis on puberty induction.
青春期是一个发育阶段,其特征是出现第二性征,从而导致身体、心理社会和性方面的完全成熟。目前对青春期男性进行激素治疗以诱导青春期的做法是基于已发表的共识和专家意见。缺乏关于男性青春期诱导最佳时机和方案的循证指南,这反映出内分泌学家在实践中存在一些差异。值得一提的是,市场上各种激素产品的可得性、它们不同的给药途径以及患者/家长的偏好也会对临床决策产生影响。本综述概述了目前对青春期延迟男孩的临床处理方法,重点是青春期诱导。