Arguni Eggi, Supriyati Endah, Hakim Mohamad Saifudin, Daniwijaya Edwin Widyanto, Makrufardi Firdian, Rahayu Ayu, Rovik Anwar, Saraswati Utari, Oktoviani Farida Nur, Prastiwi Nenes, Nuryastuti Titik, Wibawa Tri, Haryana Sofia Mubarika
Department of Child Health, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Sekip, Sleman, Yogyakarta, 55281, Indonesia.
Centre for Tropical Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Sekip, Sleman, Yogyakarta, 55281, Indonesia.
Ann Med Surg (Lond). 2022 May;77:103676. doi: 10.1016/j.amsu.2022.103676. Epub 2022 Apr 30.
Growing evidence shows that viral co-infection is found repeatedly in patients with Coronavirus Disease-2019 (COVID-19). This is the first report of SARS-CoV-2 co-infection with viral respiratory pathogens in Indonesia.
Over a one month period of April to May 2020, SARS-CoV-2 positive nasopharyngeal swabs in our COVID-19 referral laboratory in Yogyakarta, Indonesia, were tested for viral respiratory pathogens by real-time, reverse transcription polymerase chain reaction (RT-PCR). Proportion of co-infection reported in percentage.
Fifty-nine samples were positive for other viral respiratory pathogens among a total of 125 samples. Influenza A virus was detected in 32 samples, Influenza B in 16 samples, Human metapneumovirus in 1 sample, and adenovirus in 10 samples. We did not detect any co-infection with respiratory syncytial virus. Nine (7.2%) patients had co-infection with more than two viruses.
Viral co-infection with SARS-CoV-2 is common. These results will provide a helpful reference for diagnosis and clinical treatment of patients with COVID-19.
越来越多的证据表明，2019冠状病毒病（COVID-19）患者中反复出现病毒合并感染。这是印度尼西亚首例严重急性呼吸综合征冠状病毒2（SARS-CoV-2）与病毒性呼吸道病原体合并感染的报告。
在2020年4月至5月的一个月时间里，我们在印度尼西亚日惹的COVID-19转诊实验室对SARS-CoV-2阳性鼻咽拭子进行了实时逆转录聚合酶链反应（RT-PCR）检测，以确定是否存在病毒性呼吸道病原体。以百分比形式报告合并感染的比例。
在总共125份样本中，59份样本检测出其他病毒性呼吸道病原体呈阳性。32份样本中检测出甲型流感病毒，16份样本中检测出乙型流感病毒，1份样本中检测出人偏肺病毒，10份样本中检测出腺病毒。我们未检测到任何与呼吸道合胞病毒的合并感染。9名（7.2%）患者感染了两种以上病毒。
SARS-CoV-2病毒合并感染很常见。这些结果将为COVID-19患者的诊断和临床治疗提供有益参考。
