• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Treatment of Resistant Alopecia areata with Tofacitinib.

作者信息

Avhad Ganesh

机构信息

Skin and Hair World, Mumbai, Maharashtra, India.

出版信息

Int J Trichology. 2022 Mar-Apr;14(2):60-61. doi: 10.4103/ijt.ijt_128_21. Epub 2022 Apr 4.

DOI:10.4103/ijt.ijt_128_21
PMID:35531489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9069910/
Abstract

The activity of tofacitinib for Alopecia areata (AA) has been reported but mainly from the western countries. We report the case of a young female Indian patient with AA unresponsive to therapy. Improvements in terms of hair regrowth were observed within 2 months of treatment with oral tofacitinib 5 mg BID tablets. The effectiveness of tofacitinib in hair regrowth was maintained till 5-month follow-up period. There were no side effects reported and the treatment with tofacitinib was well-tolerated.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7344/9069910/9979dd2f3972/IJT-14-60-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7344/9069910/9979dd2f3972/IJT-14-60-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7344/9069910/9979dd2f3972/IJT-14-60-g001.jpg

相似文献

1
Treatment of Resistant Alopecia areata with Tofacitinib.
Int J Trichology. 2022 Mar-Apr;14(2):60-61. doi: 10.4103/ijt.ijt_128_21. Epub 2022 Apr 4.
2
Recovery of Resistant Alopecia Areata Treated with Tofacitinib: An 8-Year-Old Child's Case Report.托法替布治疗儿童斑秃疗效观察：1例8岁患儿报告
Int J Trichology. 2022 Jul-Aug;14(4):135-137. doi: 10.4103/ijt.ijt_15_22. Epub 2022 Jul 16.
3
Resistant Alopecia Areata Treated with Tofacitinib.托法替布治疗斑秃
Int J Trichology. 2022 Sep-Oct;14(5):181-182. doi: 10.4103/ijt.ijt_63_22. Epub 2022 Oct 7.
4
Janus Kinase Inhibitors for the Treatment of Severe Alopecia Areata: An Open-Label Comparative Study.Janus 激酶抑制剂治疗严重斑秃：一项开放性比较研究。
Dermatology. 2019;235(2):130-136. doi: 10.1159/000494613. Epub 2018 Dec 19.
5
Tofacitinib (Selective Janus Kinase Inhibitor 1 and 3): A Promising Therapy for the Treatment of Alopecia Areata: A Case Report of Six Patients.托法替布（选择性 Janus 激酶 1 和 3 抑制剂）：一种治疗斑秃的有前景的疗法：6 例患者的病例报告
Int J Trichology. 2018 May-Jun;10(3):103-107. doi: 10.4103/ijt.ijt_21_18.
6
Oral tofacitinib for the treatment of alopecia areata in pediatric patients.口腔托法替尼治疗儿童斑秃。
Pediatr Dermatol. 2022 Jan;39(1):31-34. doi: 10.1111/pde.14855. Epub 2021 Nov 14.
7
An Excellent Response to Tofacitinib in a Pediatric Alopecia Patient: A Case Report and Review.托法替布对一名儿童脱发患者的显著疗效：病例报告及文献复习
J Drugs Dermatol. 2018 Aug 1;17(8):914-917.
8
Refractory Alopecia Areata and Vitiligo Responding to Tofacitinib Monotherapy.难治性斑秃和白癜风对托法替尼单药治疗有反应。
J Drugs Dermatol. 2022 Dec 1;21(12):1366-1368. doi: 10.36849/JDD.6826.
9
Real-world experience and long-term evaluation of tofacitinib in refractory alopecia areata: A prospective, open-label, single-center study in Asian Arab population.在亚洲阿拉伯人群中进行的一项前瞻性、开放标签、单中心研究：托法替布治疗难治性斑秃的真实世界经验和长期评估。
Dermatol Ther. 2022 Dec;35(12):e15871. doi: 10.1111/dth.15871. Epub 2022 Dec 1.
10
Effectiveness of oral tofacitinib treatment on patients with moderate-to-severe alopecia areata in Iran.伊朗中重度斑秃患者口服托法替布治疗的疗效。
J Cosmet Dermatol. 2024 Mar;23(3):886-890. doi: 10.1111/jocd.16049. Epub 2023 Nov 7.

引用本文的文献

1
Tofacitinib in the Management of Alopecia Universalis.托法替布在全秃治疗中的应用
Int J Trichology. 2023 Sep-Oct;15(5):194-196. doi: 10.4103/ijt.ijt_77_23. Epub 2024 Jul 11.

本文引用的文献

1
Consensus on the treatment of alopecia areata - Brazilian Society of Dermatology.斑秃治疗共识 - 巴西皮肤病学会
An Bras Dermatol. 2020 Nov-Dec;95 Suppl 1(Suppl 1):39-52. doi: 10.1016/j.abd.2020.05.006. Epub 2020 Oct 8.
2
Emerging Topical and Systemic JAK Inhibitors in Dermatology.皮肤科新兴的局部和系统 JAK 抑制剂。
Front Immunol. 2019 Dec 3;10:2847. doi: 10.3389/fimmu.2019.02847. eCollection 2019.
3
JAK inhibitors for alopecia areata: a systematic review and meta-analysis.JAK 抑制剂治疗斑秃：系统评价和荟萃分析。
J Eur Acad Dermatol Venereol. 2019 May;33(5):850-856. doi: 10.1111/jdv.15489. Epub 2019 Apr 10.
4
An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis.一项开放性标签试验，旨在评估托法替尼治疗中度至重度斑状型斑秃、全秃和普秃的疗效。
J Invest Dermatol. 2018 Jul;138(7):1539-1545. doi: 10.1016/j.jid.2018.01.032. Epub 2018 Feb 13.
5
JAK inhibition as a therapeutic strategy for immune and inflammatory diseases.JAK 抑制作为治疗免疫和炎症性疾病的策略。
Nat Rev Drug Discov. 2017 Dec;16(12):843-862. doi: 10.1038/nrd.2017.201. Epub 2017 Nov 6.
6
Treatment of Alopecia Areata With Tofacitinib.他卡西醇治疗斑秃。
JAMA Dermatol. 2017 Jun 1;153(6):600-602. doi: 10.1001/jamadermatol.2017.0001.
7
JAK inhibitors in dermatology: The promise of a new drug class.皮肤科领域的JAK抑制剂：一类新药的前景
J Am Acad Dermatol. 2017 Apr;76(4):736-744. doi: 10.1016/j.jaad.2016.12.005. Epub 2017 Jan 28.
8
Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata.托法替尼枸橼酸盐治疗斑秃患者的安全性和疗效。
JCI Insight. 2016 Sep 22;1(15):e89776. doi: 10.1172/jci.insight.89776.