Internal Medicine Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Medical School, Univesity Complutense of Madrid, Madrid, Spain.
Clin Exp Hypertens. 2022 Jul 4;44(5):459-463. doi: 10.1080/10641963.2022.2071916. Epub 2022 May 8.
The role of hypertension in COVID-19 has not been clearly elucidated yet. The aim of this study was to evaluate the incidence and severity of COVID-19 in a hypertensive population and assess whether there is a link between blood pressure control and SARS-CoV-2 infection outcomes.
This was a single-center retrospective observational study that evaluated the incidence and severity of COVID-19 in a chronic hypertensive population (n=1,637) from a specialized consultation of Hypertension and Cardiovascular Risk of Internal Medicine in a tertiary hospital in Madrid (Spain).
A total of 147 COVID-19 patients (9%) were found, with a median age of 59 (±14) years, where 77 (52.4%) patients were male. Forty patients required hospitalization (27.2%), 15 patients had severe COVID-19 (10.2%), and 6 patients died (4.1%). Among the causes of hypertension, 104 (70.7%) patients had essential hypertension and 22 (15%) patients presented primary hyperaldosteronism; and 66 (44.9%) patients presented RH. Severe COVID-19 was associated with age over 65 years (crude OR 4.43 [95% CI 1.3-14.2; p = .012]) and diabetes mellitus (crude OR 4.15 [95% CI 1.3-12.9; p = .014]).
This study showed a lower rate of incidence, hospitalization, and severity of COVID-19 in the hypertensive population.
高血压在 COVID-19 中的作用尚未明确。本研究旨在评估高血压人群中 COVID-19 的发病率和严重程度，并评估血压控制与 SARS-CoV-2 感染结局之间是否存在关联。
这是一项单中心回顾性观察研究，评估了马德里（西班牙）一家三级医院内科高血压和心血管风险专科的慢性高血压人群（n=1637）中 COVID-19 的发病率和严重程度。
共发现 147 例 COVID-19 患者（9%），中位年龄为 59（±14）岁，其中 77 例（52.4%）为男性。40 例患者需要住院治疗（27.2%），15 例患者患有严重 COVID-19（10.2%），6 例患者死亡（4.1%）。在高血压的病因中，104 例（70.7%）患者为原发性高血压，22 例（15%）患者为原发性醛固酮增多症；66 例（44.9%）患者患有 RH。严重 COVID-19 与年龄超过 65 岁（粗 OR 4.43 [95% CI 1.3-14.2；p =.012]）和糖尿病（粗 OR 4.15 [95% CI 1.3-12.9；p =.014]）相关。
本研究表明高血压人群 COVID-19 的发病率、住院率和严重程度较低。
