Department of Neurosciences and Behavior, Ribeirão Preto Medical School, 54539University of São Paulo, Ribeirão Preto, SP, Brazil.
Clin Child Psychol Psychiatry. 2023 Apr;28(2):500-511. doi: 10.1177/13591045221098521. Epub 2022 May 7.
The aim of the present longitudinal study was to examine the effect of preterm childbirth, acute neonatal stress, and child behavior at 18-36 months of age on later behavior outcomes in 4-5-year-old children. The sample comprised of 70 children who were born preterm. The neonatal characteristics of children were assessed during hospitalization by reviewing their medical records and utilizing the Neonatal Infant Stressor Scale. Behavior problems were evaluated by the maternal-report in the Child Behavior Checklist 1½-5 years. A multiple linear regression analysis was conducted. Also, the repeated measures analysis of variance and the McNemar test for paired samples were performed. Daily exposure of the infants to high neonatal acute stress during NICU hospitalization and more behavior problems at 18-36 months of age was associated with more total and externalizing behavior problems at 4-5 years of age. Lower gestational age at childbirth and more internalizing behavior problems at 18-36 months was associated with more internalizing problems at 4-5 years old. The present study showed the combination of predictors of neonatal conditions and behavioral problems at childhood, highlighting the relevance of the implementation of developmental care in the NICU and follow-up the preterm infants after discharge programs.
本纵向研究的目的是探讨早产儿分娩、新生儿急性应激和 18-36 个月儿童行为对 4-5 岁儿童后期行为结果的影响。样本包括 70 名早产儿。通过回顾他们的医疗记录和使用新生儿婴儿应激量表，在住院期间评估儿童的新生儿特征。通过在儿童行为检查表 1 岁半至 5 岁期间进行母亲报告来评估行为问题。进行了多元线性回归分析。还进行了重复测量方差分析和配对样本 McNemar 检验。新生儿重症监护病房住院期间婴儿每天暴露于高急性新生儿应激和 18-36 个月时更多的行为问题与 4-5 岁时更多的总行为问题和外化行为问题相关。分娩时的胎龄较低和 18-36 个月时的更多内化行为问题与 4-5 岁时的更多内化问题相关。本研究显示了新生儿状况和儿童期行为问题预测因素的组合，突出了在新生儿重症监护病房实施发育护理以及在出院后对早产儿进行随访计划的重要性。
