IEEE Trans Med Imaging. 2022 Oct;41(10):2867-2878. doi: 10.1109/TMI.2022.3173669. Epub 2022 Sep 30.
Convolutional neural networks (CNN) have demonstrated their ability to segment 2D cardiac ultrasound images. However, despite recent successes according to which the intra-observer variability on end-diastole and end-systole images has been reached, CNNs still struggle to leverage temporal information to provide accurate and temporally consistent segmentation maps across the whole cycle. Such consistency is required to accurately describe the cardiac function, a necessary step in diagnosing many cardiovascular diseases. In this paper, we propose a framework to learn the 2D+time apical long-axis cardiac shape such that the segmented sequences can benefit from temporal and anatomical consistency constraints. Our method is a post-processing that takes as input segmented echocardiographic sequences produced by any state-of-the-art method and processes it in two steps to (i) identify spatio-temporal inconsistencies according to the overall dynamics of the cardiac sequence and (ii) correct the inconsistencies. The identification and correction of cardiac inconsistencies relies on a constrained autoencoder trained to learn a physiologically interpretable embedding of cardiac shapes, where we can both detect and fix anomalies. We tested our framework on 98 full-cycle sequences from the CAMUS dataset, which are available alongside this paper. Our temporal regularization method not only improves the accuracy of the segmentation across the whole sequences, but also enforces temporal and anatomical consistency.
卷积神经网络 (CNN) 已经证明了它们在分割 2D 心脏超声图像方面的能力。然而,尽管最近取得了成功,即在舒张末期和收缩末期图像上达到了观察者内的可变性,但 CNN 仍然难以利用时间信息在整个周期内提供准确和时间一致的分割图。这种一致性对于准确描述心脏功能是必要的,心脏功能是诊断许多心血管疾病的必要步骤。在本文中,我们提出了一种学习 2D+时间心尖长轴心脏形状的框架,使得分割的序列可以受益于时间和解剖一致性约束。我们的方法是一种后处理,它将任何最先进的方法生成的分割超声心动图序列作为输入,并分两步进行处理:(i)根据心脏序列的整体动态识别时空不一致性,(ii)纠正不一致性。心脏不一致性的识别和纠正依赖于一个受限的自动编码器,该自动编码器经过训练可以学习心脏形状的生理可解释嵌入,我们可以在其中检测和修复异常。我们在来自 CAMUS 数据集的 98 个全周期序列上测试了我们的框架,这些序列可随本文获取。我们的时间正则化方法不仅提高了整个序列的分割准确性,而且还强制了时间和解剖一致性。