Department of Psychiatry, All India Institute of Medical Sceinces, Bhubhneswar, India.
Department of Psychiatry, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Asian J Psychiatr. 2022 Jul;73:103138. doi: 10.1016/j.ajp.2022.103138. Epub 2022 Apr 26.
To determine the efficacy of individual-based, face-to-face screening and brief intervention (SBI) for hazardous alcohol use among treatment-seeking outpatients with mood disorders.
It was a parallel-group, single-blind, randomized controlled trial of 84 participants who met the selection criteria for hazardous alcohol use, defined by alcohol use disorder identification test (AUDIT) score 8-19. Participants were randomly allocated to either SBI or general advice group. Both groups had received a standard care for mood disorders. The outcome was assessed after 3 months. The primary outcome was a change in the mean AUDIT score and the secondary outcomes were a change in frequency of heavy episodic drinking and stages of motivation.
Majority (60%) had major depressive episodes. There was no significant difference in baseline demography and clinical variables between the groups. Both intention to treat and per-protocol analyses showed a small but significant effect of SBI on mean AUDIT score. Age, baseline AUDIT, and motivation did not moderate the effect. SBI was associated with a significant decrease in the frequency of heavy drinking and improvement in stages of motivation.
SBI among patients with mood disorders had a small but significant effect on alcohol use.
确定针对有心境障碍的就诊患者，个体化面对面的筛查和简短干预（SBI）对危险饮酒的疗效。
这是一项平行组、单盲、随机对照试验，共纳入 84 名符合危险饮酒筛选标准（定义为 AUDIT 评分 8-19 分）的参与者。参与者被随机分配到 SBI 或一般建议组。两组均接受了心境障碍的标准治疗。在 3 个月后评估结局。主要结局为 AUDIT 评分的平均变化，次要结局为重度饮酒频率和动机阶段的变化。
大多数（60%）患者患有重性抑郁发作。两组在基线人口统计学和临床变量方面无显著差异。意向治疗和方案分析均显示 SBI 对 AUDIT 评分有微小但显著的影响。年龄、基线 AUDIT 和动机并未调节这种影响。SBI 与重度饮酒频率的显著降低和动机阶段的改善相关。
对心境障碍患者进行 SBI 对饮酒行为有微小但显著的影响。
