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病例报告:一名感染HIV-1的患者出现播散性粪类圆线虫病,表现为溃疡性胃肿物

Case Report: Disseminated Strongloides stercoralis Presenting as an Ulcerated Gastric Mass in an HIV-1-infected Patient.

作者信息

Tameru Kassa, Tsegaye Bekure, Shikur Mohammed, Ergete Wondwossen, Tasew Geremew, Abera Adugna, Wolday Dawit

机构信息

Amin General Hospital, Addis Ababa, Ethiopia.

Department of Pathology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

Am J Trop Med Hyg. 2022 May 9;106(6):1675-7. doi: 10.4269/ajtmh.21-0791.

DOI:10.4269/ajtmh.21-0791
PMID:35533694
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9209934/
Abstract

Disseminated Strongloides stercoralis is a common phenomenon among patients with immunosuppression. In this report, we present a case of disseminated Strongloides stercoralis presenting as a gastric mass in a 42-year-old male patient with a known history of HIV-1 infection and type 2 diabetes mellitus (T2DM). The patient presented with symptoms and signs suggestive of acute on chronic erosive gastritis, which included persistent vomiting. Endoscopic examination revealed a gastric mass with no signs of malignancy or dysplasia. There was noted to be chronic inflammation along with morphologic features consistent with the larvae and eggs of Strongloides nematodes in a biopsied gastric mass tissue and duodenum. The disease subsequently resulted in death despite the administration of ivermectin.

摘要

播散性粪类圆线虫病在免疫抑制患者中很常见。在本报告中,我们介绍了一例播散性粪类圆线虫病病例,该病例表现为一名42岁男性患者的胃肿物,该患者有HIV-1感染和2型糖尿病(T2DM)病史。患者出现提示急性慢性糜烂性胃炎的症状和体征,包括持续性呕吐。内镜检查发现一个胃肿物,无恶性或发育异常迹象。在活检的胃肿物组织和十二指肠中发现有慢性炎症以及与粪类圆线虫幼虫和虫卵一致的形态学特征。尽管给予了伊维菌素治疗,该疾病最终仍导致患者死亡。

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