Sharma R C, Parashar R K
J Inorg Biochem. 1987 Mar;29(3):225-30. doi: 10.1016/0162-0134(87)80029-6.
Binary as well as ternary complexes of Zn(II) with diphenylamine-2,2'-dicarboxylic acid (dpdc), diphenylamine-2-amino-2'-carboxylic acid (dpac), diphenylamine-2-hydroxy-2'-carboxylic acid (dphc), diphenylamine-2-mercapto-2'-carboxylic acid (dpmc), and N-(2-pyridino) anthranilic acid (npa) have been synthesized and characterized by their elemental analysis, IR spectral data, and molar conductance measurements. Antimicrobial activity of these ligands and their respective Zn(II) complexes have been determined on gram positive (Staphylococcus aureus) and gram negative (Escherichia coli) bacteria and on Aspergillus niger and Aspergillus nidulense, two common fungi by the serial dilution method. A considerable increase in the biocidal activity of these ligands on being coordinated with the metal ion has been reported in terms of their minimum inhibitory concentration (MIC) values.
已合成了锌（II）与二苯胺 - 2,2'-二羧酸（dpdc）、二苯胺 - 2 - 氨基 - 2'-羧酸（dpac）、二苯胺 - 2 - 羟基 - 2'-羧酸（dphc）、二苯胺 - 2 - 巯基 - 2'-羧酸（dpmc）以及N - （2 - 吡啶基）邻氨基苯甲酸（npa）形成的二元和三元配合物，并通过元素分析、红外光谱数据和摩尔电导率测量对其进行了表征。通过系列稀释法测定了这些配体及其各自的锌（II）配合物对革兰氏阳性菌（金黄色葡萄球菌）、革兰氏阴性菌（大肠杆菌）以及两种常见真菌黑曲霉和构巢曲霉的抗菌活性。根据它们的最低抑菌浓度（MIC）值报道了这些配体与金属离子配位后杀菌活性有显著提高。
