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新型冠状病毒肺炎后非小细胞肺癌肺切除术后的早期结果

Early outcomes of lung resections in non-small cell lung cancer after COVID-19 pneumonia.

作者信息

Hekimoglu Baris, Beyoglu Muhammet Ali

机构信息

Department of Thoracic Surgery, Faculty of Medicine, University of Ordu, Ordu, Turkey.

Department of General Thoracic Surgery and Lung Transplantation, Ankara City Hospital, University of Health Sciences, Ankara, Turkey.

出版信息

Asian J Surg. 2022 Aug;45(8):1553-1558. doi: 10.1016/j.asjsur.2022.04.080. Epub 2022 May 2.

DOI:10.1016/j.asjsur.2022.04.080
PMID:35534331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9057984/
Abstract

OBJECTIVE

There is limited literature on patients with a history of COVID-19 pneumonia who underwent anatomical lung resection for non-small cell lung cancer (NSCLC). This study was aimed to share the early postoperative outcomes in patients who underwent lung resection after COVID-19 pneumonia.

MATERIALS AND METHODS

We retrospectively evaluated 30 patients who underwent lobectomy with thoracotomy and systematic mediastinal lymph node dissection due to NSCLC in a single center between November 2018 and September 2021. The patients were divided into two groups regarding COVID-19 pneumonia history; the COVID-19 group consisted of 14 patients (46.7%) and the non-COVID-19 group 16 (53.3%) patients. The patients' age, gender, comorbidity, Charlson Comorbidity Index (CCI) score, forced expiratory volume in 1 s (FEV1) value, tumor type and size, resection type, postoperative air leak duration, total drainage volume, drain removal time, postoperative complications, and length of stay (LOS) were recorded.

RESULTS

9 (30%) patients were female, and 21 (70%) were male. The mean age was 62.1 ± 8.91 years. Our comparison of postoperative air leak duration, total drainage volume, time to drain removal, postoperative complications, and LOS between the COVID-19 and non-COVID-19 groups revealed no statistically significant difference.

CONCLUSION

Anatomical lung resection can be performed safely in NSCLC patients with a history of COVID-19 pneumonia without significant difference in early postoperative morbidity and mortality.

摘要

目的

关于曾患新型冠状病毒肺炎(COVID-19肺炎)并接受非小细胞肺癌(NSCLC)解剖性肺切除术的患者的文献有限。本研究旨在分享COVID-19肺炎后接受肺切除术患者的早期术后结果。

材料与方法

我们回顾性评估了2018年11月至2021年9月期间在单一中心因NSCLC接受开胸肺叶切除术及系统性纵隔淋巴结清扫术的30例患者。根据COVID-19肺炎病史将患者分为两组;COVID-19组有14例患者(46.7%),非COVID-19组有16例患者(53.3%)。记录患者的年龄、性别、合并症、查尔森合并症指数(CCI)评分、一秒用力呼气容积(FEV1)值、肿瘤类型和大小、切除类型、术后漏气持续时间、总引流量、引流管拔除时间、术后并发症及住院时间(LOS)。

结果

9例(30%)患者为女性,21例(70%)为男性。平均年龄为62.1±8.91岁。我们对COVID-19组和非COVID-19组之间的术后漏气持续时间、总引流量、引流管拔除时间、术后并发症及LOS进行比较,结果显示无统计学显著差异。

结论

对于有COVID-19肺炎病史的NSCLC患者,可安全地进行解剖性肺切除术,术后早期发病率和死亡率无显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769f/9057984/661ae2ac1da0/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769f/9057984/ec1f4464de3a/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769f/9057984/661ae2ac1da0/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769f/9057984/ec1f4464de3a/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769f/9057984/661ae2ac1da0/gr2_lrg.jpg

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